ProRule PRU00436

General rule information [?]

Accession PRU00436
Dates 6-MAY-2005 (Created)
27-JUN-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51080; CTF_NFI_2
Name CTF/NF-I DNA-binding domain
Function The CTF/NF-I DNA-binding domain contains four conserved Cys residues, which are required for its DNA-binding activity.
Scope(s) Eukaryota
Example(s) Q12857 (NFIA_HUMAN);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the CTF/NF-I family.

Keywords [?]

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0006260; Biological process:DNA replication
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS00349; CTF_NFI_1; 1;

Features [?]

From: PS51080
Key From To Description Tag Condition FTGroup
DNA_BIND from to /note="CTF/NF-I #"

Additional information [?]

Size range 190-195 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]