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annotation rule: PRU00436

General rule information [?]

Accession PRU00436
Dates 6-MAY-2005 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51080; CTF_NFI_2
Name CTF/NF-I DNA-binding domain
Function The CTF/NF-I DNA-binding domain contains four conserved Cys residues, which are required for its DNA-binding activity.

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.
Similarity Belongs to the CTF/NF-I family.

Cross-references [?]

PROSITE PS00349; CTF_NFI_1; 1;

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0006260; Biological process: DNA replication.
GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:0006351; Biological process: transcription, DNA-templated.

Keywords [?]

Features [?]

From: PS51080
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     from     to       CTF/NF-I #        

Additional information [?]

Size range 190-195 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example Q12857 (NFIA_HUMAN)
Eukaryota; Metazoa


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [19]