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ProRule PRU00450


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00450
Accession PRU00450
Dates 28-JUN-2005 (Created)
19-NOV-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS50876; ZF_INTEGRASE
Name Zinc finger integrase-type
Function required for integration activity and enhances tetramerization in the context of the full-length integrase.
Scope(s) Eukaryota
Viruses
Example(s) P51517 (POL_SRV2);

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS50876:10=[CH]> and <Feature:PS50876:14=[CH]> and <Feature:PS50876:38=[CH]> and <Feature:PS50876:41=[CH]>
Zinc
Metal-binding
end case

Features [?]

From: PS50876
Key From To Description Tag Condition FTGroup
case <Feature:PS50876:10=[H]> and <Feature:PS50876:14=[H]> and <Feature:PS50876:38=[C]> and <Feature:PS50876:41=[C]>
ZN_FING from to /note="Integrase-type #"
else case <Feature:PS50876:10=[CH]> and <Feature:PS50876:14=[CH]> and <Feature:PS50876:38=[CH]> and <Feature:PS50876:41=[CH]>
ZN_FING from to /note="Integrase-type #; atypical"
else
ZN_FING from to /note="Integrase-type #; degenerate"
end case
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 14 14 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 38 38 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 41 41 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 30-54 amino acids
Related rules None
Fusion None
Repeats 1-3
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]