ProRule PRU00450
General rule information
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Accession | PRU00450 |
Dates | 28-JUN-2005 (Created)
19-NOV-2022 (Last updated, Version 9) |
Data class | Domain; |
Predictors |
PROSITE; PS50876; ZF_INTEGRASE |
Name | Zinc finger integrase-type |
Function | required for integration activity and enhances tetramerization in the context of the full-length integrase. |
Scope(s) |
Eukaryota Viruses |
Example(s) | P51517 (POL_SRV2); |
Propagated annotation
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Keywords
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Zinc-finger | |
case <Feature:PS50876:10=[CH]> and <Feature:PS50876:14=[CH]> and <Feature:PS50876:38=[CH]> and <Feature:PS50876:41=[CH]> | |
Zinc | |
Metal-binding | |
end case |
Features
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From: PS50876 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
case <Feature:PS50876:10=[H]> and <Feature:PS50876:14=[H]> and <Feature:PS50876:38=[C]> and <Feature:PS50876:41=[C]> | ||||||||||||
ZN_FING | from | to | /note="Integrase-type #" | |||||||||
else case <Feature:PS50876:10=[CH]> and <Feature:PS50876:14=[CH]> and <Feature:PS50876:38=[CH]> and <Feature:PS50876:41=[CH]> | ||||||||||||
ZN_FING | from | to | /note="Integrase-type #; atypical" | |||||||||
else | ||||||||||||
ZN_FING | from | to | /note="Integrase-type #; degenerate" | |||||||||
end case | ||||||||||||
BINDING | 10 | 10 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
BINDING | 14 | 14 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
BINDING | 38 | 38 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
BINDING | 41 | 41 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 |
Additional information
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Size range | 30-54 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1-3 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [10] Viruses [94] All [ 104 ]
- Retrieve set of proteins with 3D structure for this domain