ProRule PRU00451
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00451
General rule information
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| Accession | PRU00451 |
| Dates | 28-JUN-2005 (Created)
19-NOV-2022 (Last updated, Version ) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51036; ZF_A20 |
Name | Zinc finger A20-type |
| Function | Functions as a ubiquitin ligase by polyubiquitinating RIP with Lys- 48-linked ubiquitin chains. |
| Scope(s) |
Eukaryota Mammalia |
| Example(s) | P21580; |
Propagated annotation
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Keywords
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| Zinc-finger | |
| case <Feature:PS51036:7=[CH]> and <Feature:PS51036:11=[CH]> and <Feature:PS51036:23=[CH]> and <Feature:PS51036:26=[CH]> | |
| Zinc | |
| Metal-binding | |
| end case | |
Features
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| From: PS51036 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51036:7=[C]> and <Feature:PS51036:11=[C]> and <Feature:PS51036:23=[C]> and <Feature:PS51036:26=[C]> | ||||||||||||
| ZN_FING | from | to | /note="A20-type #" | |||||||||
| else case <Feature:PS51036:7=[CH]> and <Feature:PS51036:11=[CH]> and <Feature:PS51036:23=[CH]> and <Feature:PS51036:26=[CH]> | ||||||||||||
| ZN_FING | from | to | /note="A20-type #. atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | to | /note="A20-type #; degenerate" | |||||||||
| end case | ||||||||||||
| BINDING | 7 | 7 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 11 | 11 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 23 | 23 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 26 | 26 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
Additional information
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| Size range | 32-34 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-7 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [48] All [ 48 ]
- Retrieve set of proteins with 3D structure for this domain