PROSITE logo

ProRule PRU00451


General rule information [?]

Accession PRU00451
Dates 28-JUN-2005 (Created)
19-NOV-2022 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51036; ZF_A20
Name Zinc finger A20-type
Function Functions as a ubiquitin ligase by polyubiquitinating RIP with Lys- 48-linked ubiquitin chains.
Scope(s) Eukaryota
Mammalia
Example(s) P21580 (TNAP3_HUMAN);

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS51036:7=[CH]> and <Feature:PS51036:11=[CH]> and <Feature:PS51036:23=[CH]> and <Feature:PS51036:26=[CH]>
Zinc
Metal-binding
end case

Features [?]

From: PS51036
Key From To Description Tag Condition FTGroup
case <Feature:PS51036:7=[C]> and <Feature:PS51036:11=[C]> and <Feature:PS51036:23=[C]> and <Feature:PS51036:26=[C]>
ZN_FING from to /note="A20-type #"
else case <Feature:PS51036:7=[CH]> and <Feature:PS51036:11=[CH]> and <Feature:PS51036:23=[CH]> and <Feature:PS51036:26=[CH]>
ZN_FING from to /note="A20-type #. atypical"
else
ZN_FING from to /note="A20-type #; degenerate"
end case
BINDING 7 7 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 11 11 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 23 23 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 26 26 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 32-34 amino acids
Related rules None
Fusion None
Repeats 1-7
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



View rule in raw text format (no links)

UniProtKB rule member sequences [?]