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ProRule PRU00455


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00455
Accession PRU00455
Dates 29-JUN-2005 (Created)
19-NOV-2022 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51081; ZF_SIAH
Name Zinc finger SIAH-type
Function substrate- and cofactor-interaction domain
Scope(s) Eukaryota
Example(s) Q8R4T2 (SIAH2_RAT);

Propagated annotation [?]

Keywords [?]

Zinc-finger
case (<Feature:PS50089:6=[CH]> and <Feature:PS50089:13=[CH]> and <Feature:PS50089:25=[CH]> and <Feature:PS50089:29=[CH]>) or (<Feature:PS50089:36=[CH]> and <Feature:PS50089:43=[CH]> and <Feature:PS50089:55=[CH]> and <Feature:PS50089:60=[CH]>)
Zinc
Metal-binding
end case
case <Feature:PS50089:6=[C]> and <Feature:PS50089:13=[C]> and <Feature:PS50089:25=[H]> and <Feature:PS50089:29=[C]> and <Feature:PS50089:36=[C]> and <Feature:PS50089:43=[C]> and <Feature:PS50089:55=[H]> and <Feature:PS50089:60=[H]>
else case <Feature:PS50089:6=[CH]> and <Feature:PS50089:13=[CH]> and <Feature:PS50089:25=[CH]> and <Feature:PS50089:29=[CH]> and <Feature:PS50089:36=[CH]> and <Feature:PS50089:43=[CH]> and <Feature:PS50089:55=[CH]> and <Feature:PS50089:60=[CH]>

Features [?]

From: PS51081
Key From To Description Tag Condition FTGroup
case <Feature:PS50089:6=[C]> and <Feature:PS50089:13=[C]> and <Feature:PS50089:25=[H]> and <Feature:PS50089:29=[C]> and <Feature:PS50089:36=[C]> and <Feature:PS50089:43=[C]> and <Feature:PS50089:55=[H]> and <Feature:PS50089:60=[H]>
ZN_FING from to /note="SIAH-type #"
else case <Feature:PS50089:6=[CH]> and <Feature:PS50089:13=[CH]> and <Feature:PS50089:25=[CH]> and <Feature:PS50089:29=[CH]> and <Feature:PS50089:36=[CH]> and <Feature:PS50089:43=[CH]> and <Feature:PS50089:55=[CH]> and <Feature:PS50089:60=[CH]>
ZN_FING from to /note="SIAH-type #; atypical"
else
ZN_FING from to /note="SIAH-type #; degenerate"
end case
BINDING 6 6 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 13 13 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 25 25 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 29 29 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 36 36 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 43 43 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 55 55 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 60 60 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2

Additional information [?]

Size range 50-70 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]