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| annotation rule: PRU00456 |
General rule information
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| Accession | PRU00456 |
| Dates | 29-JUN-2005 (Created) 14-MAY-2022 (Last updated, Version 8) |
| Data class | Domain |
| Predictors | PROSITE; PS51074; DPH_MB |
| Names | DPH-type metal-binding (MB) domain; CSL-type MB domain |
| Function | The DHP-type or CSL-type MB domain contains a Cys-X-Cys...Cys-X2-Cys motif which tetrahedrically coordinates either Fe or Zn, but Zn is much more tightly bound. |
Propagated annotation
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Comments
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case <FTGroup:1>
| Domain | The DPH-type metal-binding (MB) domain can bind either zinc or iron ions. |
Keywords
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end case
Features
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| From: PS51074 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | DPH-type MB # | |||||||||
| BINDING | 23 | 23 | /ligand="Zn(2+)" /ligand_id="29105 | C | 1 | |||||||
| BINDING | 25 | 25 | /ligand="Zn(2+)" /ligand_id="29105 | C | 1 | |||||||
| BINDING | 45 | 45 | /ligand="Zn(2+)" /ligand_id="29105 | C | 1 | |||||||
| BINDING | 48 | 48 | /ligand="Zn(2+)" /ligand_id="29105 | C | 1 | |||||||
Additional information
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| Size range | 50-75 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q6VUC1 (DPH3_CRIGR) |
| Scope | Eukaryota |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [40]
- Retrieve set of proteins with 3D structure for this domain