PRU00456

General rule information [?]

Accession	PRU00456
Dates	29-JUN-2005 (Created) 19-NOV-2022 (Last updated, Version 9)

Data class

Domain

Predictors

PROSITE; PS51074; DPH_MB

Names

DPH-type metal-binding (MB) domain; CSL-type MB domain

Function

The DHP-type or CSL-type MB domain contains a Cys-X-Cys...Cys-X2-Cys motif which tetrahedrically coordinates either Fe or Zn, but Zn is much more tightly bound.

Propagated annotation [?]

Comments [?]

case <FTGroup:1>

Domain

The DPH-type metal-binding (MB) domain can bind either zinc or iron ions.

Keywords [?]

Metal-binding
Iron
Zinc

end case

Features [?]

From: PS51074

Key From To Description Tag Condition FTGroup

DOMAIN from to DPH-type MB #

BINDING 23 23 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

BINDING 25 25 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

BINDING 45 45 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

BINDING 48 48 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

Additional information [?]

Size range	50-75 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	Q6VUC1 (DPH3_CRIGR)
Scope	Eukaryota

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Eukaryota [40]
Retrieve set of proteins with 3D structure for this domain