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annotation rule: PRU00456 |
General rule information
[?]
Accession |
PRU00456 |
Dates |
29-JUN-2005 (Created) 14-MAY-2022 (Last updated, Version 8) |
Predictors |
PROSITE; PS51074; DPH_MB
|
Names |
DPH-type metal-binding (MB) domain; CSL-type MB domain |
Function |
The DHP-type or CSL-type MB domain contains a Cys-X-Cys...Cys-X2-Cys motif which tetrahedrically coordinates either Fe or Zn, but Zn is much more tightly bound. |
Propagated annotation
[?]
case <FTGroup:1>
Domain |
The DPH-type metal-binding (MB) domain can bind either zinc or iron ions. |
end case
From: PS51074 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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DOMAIN
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from
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to
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DPH-type MB #
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BINDING
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23
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23
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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BINDING
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25
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25
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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BINDING
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45
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45
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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BINDING
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48
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48
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/ligand="Zn(2+)" /ligand_id="29105
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C
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1
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Additional information
[?]
Size range |
50-75 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
Q6VUC1 (DPH3_CRIGR) |
Scope |
Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]