ProRule PRU00457

General rule information [?]

Accession PRU00457
Dates 29-JUN-2005 (Created)
27-MAR-2023 (Last updated, Version 12)
Data class Domain;
Predictors PROSITE; PS50994; INTEGRASE
Name Integrase catalytic domain
Function The integrase catalytic domain catalyzes a series of reactions to integrate the viral genome into a host chromosome.
Scope(s) Eukaryota
Example(s) O92956 (POL_RSVSB);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0004518; Molecular function:nuclease activity
GO:0004519; Molecular function:endonuclease activity
GO:0016787; Molecular function:hydrolase activity
GO:0006310; Molecular function:DNA recombination
GO:0006313; Molecular function:DNA transposition
end case

Features [?]

From: PS50994
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Integrase catalytic #"
BINDING 12 12 /ligand="Mg(2+)"
D 1
BINDING 71 71 /ligand="Mg(2+)"
D 1

Additional information [?]

Size range 43-217 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]