General rule information
[?]
Accession |
PRU00463 |
Dates |
30-JUN-2005 (Created) 21-NOV-2019 (Last updated, Version 8) |
Function |
a membrane binding motif which, in the presence of calcium ions, interacts with phospholipid membranes that include phosphatidylserine |
Propagated annotation
[?]
case <FTGroup:1> or <FTGroup:2>
Ptm |
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
end case
case <FTGroup:1> or <FTGroup:2>
GO:0005509; Molecular function: calcium ion binding.
end case
case <FTGroup:1> or <FTGroup:2>
end case
case <FTTag:disulf>
end case
From: PS50998 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
Gla #
|
|
|
|
|
|
|
MOD_RES
|
|
21
|
|
21
|
|
4-carboxyglutamate
|
|
|
|
E
|
|
1
|
MOD_RES
|
|
24
|
|
24
|
|
4-carboxyglutamate
|
|
|
|
E
|
|
2
|
DISULFID
|
|
18
|
|
23
|
|
|
|
disulf
|
|
C-x*-C
|
|
|
DISULFID
|
|
23
|
|
29
|
|
|
|
disulf
|
|
C-x*-C
|
|
|
Additional information
[?]
Size range |
17-45 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
P84349 (OSTCN_GORGO) |
Scope |
Eukaryota; Gnathostomata |
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distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]