ProRule PRU00480
General rule information
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Accession | PRU00480 |
Dates | 26-AUG-2005 (Created)
19-NOV-2022 (Last updated, Version 11) |
Data class | Domain; |
Predictors |
PROSITE; PS51130; PDXT_SNO_2 |
Name | PdxT/SNO family |
Function | PdxS/SNZ and pdxT/SNO proteins form a complex which serves as a glutamine amidotransferase to supply ammonia as a source of the ring nitrogen of vitamin B6. PdxT/SNO appear to encode the glutaminase subunit, which produces ammonia from glutamine. |
Scope(s) |
Eukaryota Bacteria Archaea |
Example(s) | Q03144 (SNO1_YEAST); |
Propagated annotation
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Identifier, protein and gene names
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case <FT:1> | |
Protein name | AltName: Full=Probable glutamine amidotransferase; EC=2.6.-.-; |
end case |
Comments
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SIMILARITY | Belongs to the glutamine amidotransferase pdxT/SNO family. |
Keywords
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case <FT:1> | |
Glutamine amidotransferase | |
Transferase | |
end case | |
case <OC:Bacteria> or <OG:Archaea> | |
Pyridoxal phosphate | |
end case | |
case <OC:Eukaryota> | |
Pyridoxine biosynthesis | |
end case |
Gene Ontology
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case <FT:1> | |
GO:0006541; Biological process:glutamine metabolic process | |
GO:0016740; Molecular function:transferase activity | |
end case | |
case <OCellular component:Eukaryota> and <FT:1> | |
GO:0008615; Biological process:pyridoxine biosynthetic process | |
end case |
Cross-references
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PROSITE | PS01236; PDXT_SNO_1; 1; |
Features
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From: PS51130 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 79 | 79 | /note="Nucleophile" | C | ||||||||
case <Feature:PS51130:79=C> | ||||||||||||
ACT_SITE | 176 | 176 | H | |||||||||
ACT_SITE | 178 | 178 | E | |||||||||
end case | ||||||||||||
BINDING | 111 | 111 | /ligand="L-glutamine" /ligand_id="ChEBI:CHEBI:58359" |
R |
Additional information
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Size range | 170-215 amino acids |
Related rules |
PRU00605 PRU00606 |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [61] Bacteria [183] Eukaryota [8] All [ 252 ]
- Retrieve set of proteins with 3D structure for this domain