ProRule PRU00480
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PURL: https://purl.expasy.org/prosite/rule/PRU00480
General rule information
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| Accession | PRU00480 |
| Dates | 26-AUG-2005 (Created)
19-NOV-2022 (Last updated, Version 12) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51130; PDXT_SNO_2 |
Name | PdxT/SNO family |
| Function | PdxS/SNZ and pdxT/SNO proteins form a complex which serves as a glutamine amidotransferase to supply ammonia as a source of the ring nitrogen of vitamin B6. PdxT/SNO appear to encode the glutaminase subunit, which produces ammonia from glutamine. |
| Scope(s) |
Eukaryota Bacteria Archaea |
| Example(s) | Q03144; |
Propagated annotation
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Identifier, protein and gene names
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| case <FT:1> | |
| Protein name | AltName: Full=Probable glutamine amidotransferase; EC=2.6.-.-; |
| end case | |
Comments
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| SIMILARITY | Belongs to the glutamine amidotransferase pdxT/SNO family. |
Keywords
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| case <FT:1> | |
| Glutamine amidotransferase | |
| Transferase | |
| end case | |
| case <OC:Bacteria> or <OG:Archaea> | |
| Pyridoxal phosphate | |
| end case | |
| case <OC:Eukaryota> | |
| Pyridoxine biosynthesis | |
| end case | |
Gene Ontology
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| case <FT:1> | |
| GO:0006541; Biological process:glutamine metabolic process | |
| GO:0016740; Molecular function:transferase activity | |
| end case | |
| case <OCellular component:Eukaryota> and <FT:1> | |
| GO:0008615; Biological process:pyridoxine biosynthetic process | |
| end case | |
Cross-references
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| PROSITE | PS01236; PDXT_SNO_1; 1; |
Features
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| From: PS51130 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 79 | 79 | /note="Nucleophile" | C | ||||||||
| case <Feature:PS51130:79=C> | ||||||||||||
| ACT_SITE | 176 | 176 | H | |||||||||
| ACT_SITE | 178 | 178 | E | |||||||||
| end case | ||||||||||||
| BINDING | 111 | 111 | /ligand="L-glutamine" /ligand_id="ChEBI:CHEBI:58359" |
R | ||||||||
Additional information
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| Size range | 170-215 amino acids |
| Related rules |
PRU00605 PRU00606 |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [61] Bacteria [183] Eukaryota [8] All [ 252 ]
- Retrieve set of proteins with 3D structure for this domain