We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00524
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00524
General rule information
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| Accession | PRU00524 |
| Dates | 22-DEC-2005 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51177; LUMAZINE_BIND |
Name | Riboflavin synthase alpha chain lumazine-binding repeat |
| Function | Riboflavin synthase, catalyzing the biosynthesis of riboflavin (vitamin B2) by dismutation of 6,7-dimethyl-8-(1'-D-ribityl)lumazine (Lum) (EC 2.5.1.9), and antenna proteins involved in bioluminescence of marine bacteria seem to have evolved from the duplication of a domain of about 100 residues, the lumazine-binding repeat. |
| Scope(s) |
Bacteria Eukaryota Fungi Viridiplantae Archaea |
| Example(s) | P0AFU8; |
Propagated annotation
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Features
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| From: PS51177 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REPEAT | entry | exit | /note="Lumazine-binding #" | |||||||||
Additional information
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| Size range | 80-110 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [23] Eukaryota [3] All [ 26 ]
- Retrieve set of proteins with 3D structure for this domain