annotation rule: PRU00532

General rule information [?]

Accession PRU00532
Dates 16-MAR-2006 (Created)
16-DEC-2016 (Last updated, Version 11)
Data class Domain
Predictors PROSITE; PS51186; GNAT
Predictors PROSITE; PS51729; GNAT_YJDJ
Predictors PROSITE; PS51730; GNAT_ATAT
Predictors PROSITE; PS51731; GNAT_NAGS
Name Gcn5-related N-acetyltransferase (GNAT) domain
Function The GNAT domain catalyzes the transfer of an acetyl group from the CoA donor to a primary amine of the acceptor, a reaction implicated in various functions from bacterial antibiotic resistance to mammalian circadian rhythm and chromatin remodeling.

Propagated annotation [?]


Description [?]

+ RecName: EC=2.3.1.-;

Gene Ontology [?]

GO:0016407; Molecular function: acetyltransferase activity.
GO:0016740; Molecular function: transferase activity.

Keywords [?]


Features [?]

From: any
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     entry     exit       N-acetyltransferase #        

Additional information [?]

Size range 80-210 amino acids
Related rules PRU00533; PRU00536
Repeats 1-3
Topology Undefined
Example Q92831 (KAT2B_HUMAN)
Scope Bacteria
Eukaryota
Archaea
Viruses

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]