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annotation rule: PRU00532

General rule information [?]

Accession PRU00532
Dates 16-MAR-2006 (Created)
21-NOV-2019 (Last updated, Version 12)
Data class Domain
Predictors PROSITE; PS51186; GNAT
Predictors PROSITE; PS51729; GNAT_YJDJ
Predictors PROSITE; PS51730; GNAT_ATAT
Predictors PROSITE; PS51731; GNAT_NAGS
Name Gcn5-related N-acetyltransferase (GNAT) domain
Function The GNAT domain catalyzes the transfer of an acetyl group from the CoA donor to a primary amine of the acceptor, a reaction implicated in various functions from bacterial antibiotic resistance to mammalian circadian rhythm and chromatin remodeling.

Propagated annotation [?]

Description [?]

+ RecName: EC 2.3.1.-;

Gene Ontology [?]

GO:0016407; Molecular function: acetyltransferase activity.
GO:0016740; Molecular function: transferase activity.

Keywords [?]

Features [?]

From: any
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     entry     exit       N-acetyltransferase #        

Additional information [?]

Size range 80-210 amino acids
Related rules PRU00533; PRU00536
Repeats 1-3
Topology Undefined
Example Q92831 (KAT2B_HUMAN)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]