We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00532
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00532
General rule information
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| Accession | PRU00532 |
| Dates | 16-MAR-2006 (Created)
21-NOV-2019 (Last updated, Version 13) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51186; GNAT PROSITE; PS51729; GNAT_YJDJ PROSITE; PS51730; GNAT_ATAT PROSITE; PS51731; GNAT_NAGS |
Name | Gcn5-related N-acetyltransferase (GNAT) domain |
| Function | The GNAT domain catalyzes the transfer of an acetyl group from the CoA donor to a primary amine of the acceptor, a reaction implicated in various functions from bacterial antibiotic resistance to mammalian circadian rhythm and chromatin remodeling. |
| Scope(s) |
Bacteria Eukaryota Archaea Viruses |
| Example(s) | Q92831; |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=2.3.1.-; |
Keywords
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Gene Ontology
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| GO:0016407; Molecular function:acetyltransferase activity |
| GO:0016740; Molecular function:transferase activity |
Features
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| From: any | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | entry | exit | /note="N-acetyltransferase #" | |||||||||
Additional information
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| Size range | 80-210 amino acids |
| Related rules |
PRU00533 PRU00536 |
| Fusion | None |
| Repeats | 1-3 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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