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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00575


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00575
General rule information [?]

Accession PRU00575
Dates 10-JUL-2006 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51226; TEP1_N
Name TEP1 N-terminal repeat
Function The TEP1 N-terminal repeat is a 30 residue module whereof 4 tandemly arranged copies form the N-terminus of telomerase protein component 1 (TP1) or TEP1, which is a protein component of two ribonucleoprotein (RNP) complexes: vaults and telomerase.
Scope(s) Eukaryota
Craniata
Example(s) Q99973;

Propagated annotation [?]

Keywords [?]

Chromosome
Ribonucleoprotein
Telomere

Gene Ontology [?]

GO:0005694; Cellular component:chromosome
GO:1990904; Cellular component:ribonucleoprotein complex
GO:0007004; Cellular component:telomere maintenance via telomerase
GO:0000781; Cellular component:chromosome, telomeric region

Features [?]

From: PS51226
Key From To Description Tag Condition FTGroup
REPEAT entry exit /note="TEP1 N-terminal #"

Additional information [?]

Size range 25-35 amino acids
Related rules None
Fusion None
Repeats 4
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]