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| annotation rule: PRU00577 |
General rule information
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| Accession | PRU00577 |
| Dates | 14-JUL-2006 (Created) 21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain |
| Predictors | PROSITE; PS51231; DAD |
| Names | Diaphanous autoregulatory domain (DAD); DRF autoregulatory domain; Diaphanous autoinhibitory domain |
| Function | The DAD domain is a ~32 amino acid autoinhibitory domain in diaphanous-related formins (DRF), which inhibits the activity of the DRF catalytical formin homology 2 (FH2) domain to nucleate and elongate nonbranched actin filaments. |
Propagated annotation
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Features
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| From: PS51231 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | DAD # | |||||||||
Additional information
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| Size range | 20-40 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q9Z207 (DIAP3_MOUSE) |
| Scope | Eukaryota |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [40]
- Retrieve set of proteins with 3D structure for this domain