ProRule PRU00577

General rule information [?]

Accession PRU00577
Dates 14-JUL-2006 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51231; DAD
Name Diaphanous autoregulatory domain (DAD)
Function The DAD domain is a ~32 amino acid autoinhibitory domain in diaphanous-related formins (DRF), which inhibits the activity of the DRF catalytical formin homology 2 (FH2) domain to nucleate and elongate nonbranched actin filaments.
Scope(s) Eukaryota
Example(s) Q9Z207 (DIAP3_MOUSE);

Propagated annotation [?]

Features [?]

From: PS51231
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="DAD #"

Additional information [?]

Size range 20-40 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]