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annotation rule: PRU00577 |
Accession | PRU00577 |
Dates | 14-JUL-2006 (Created) 21-NOV-2019 (Last updated, Version 3) |
Data class | Domain |
Predictors | PROSITE; PS51231; DAD |
Names | Diaphanous autoregulatory domain (DAD); DRF autoregulatory domain; Diaphanous autoinhibitory domain |
Function | The DAD domain is a ~32 amino acid autoinhibitory domain in diaphanous-related formins (DRF), which inhibits the activity of the DRF catalytical formin homology 2 (FH2) domain to nucleate and elongate nonbranched actin filaments. |
From: PS51231 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | DAD # |
Size range | 20-40 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q9Z207 (DIAP3_MOUSE) |
Scope | Eukaryota |
Eukaryota | [40] |