 |
|
| annotation rule: PRU00577 |
General rule information
[?]
| Accession | PRU00577 |
| Dates | 14-JUL-2006 (Created) 16-DEC-2016 (Last updated, Version 2) |
| Data class | Domain |
| Predictors | PROSITE; PS51231; DAD |
| Names | Diaphanous autoregulatory domain (DAD); DRF autoregulatory domain; Diaphanous autoinhibitory domain |
| Function | The DAD domain is a ~32 amino acid autoinhibitory domain in diaphanous-related formins (DRF), which inhibits the activity of the DRF catalytical formin homology 2 (FH2) domain to nucleate and elongate nonbranched actin filaments. |
Propagated annotation
[?]
Features
[?]
| From: PS51231 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | DAD # | |||||||||
Additional information
[?]
| Size range | 20-40 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q9Z207 (DIAP3_MOUSE) |
| Scope | Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
-
UniProtKB/Swiss-Prot sets
Eukaryota [40]
- Retrieve set of proteins with 3D structure for this domain