ProRule PRU00577
General rule information
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| Accession | PRU00577 |
| Dates | 14-JUL-2006 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51231; DAD |
Name | Diaphanous autoregulatory domain (DAD) |
| Function | The DAD domain is a ~32 amino acid autoinhibitory domain in diaphanous-related formins (DRF), which inhibits the activity of the DRF catalytical formin homology 2 (FH2) domain to nucleate and elongate nonbranched actin filaments. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9Z207 (DIAP3_MOUSE); |
Propagated annotation
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Features
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| From: PS51231 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="DAD #" | |||||||||
Additional information
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| Size range | 20-40 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [40] All [ 40 ]
- Retrieve set of proteins with 3D structure for this domain