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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00583


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00583
General rule information [?]

Accession PRU00583
Dates 12-SEP-2006 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51253; HTH_CENPB
Name CENPB-type HTH domain
Function The CENPB-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 70-75 amino acids, present in eukaryotic centromere proteins and transposases.
Scope(s) Eukaryota
Example(s) P07199;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

DNA-binding
Nucleus

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus

Features [?]

From: PS51253
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HTH CENPB-type #"
DNA_BIND 34 64 /note="H-T-H motif"

Additional information [?]

Size range 60-85 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]