ProRule PRU00583
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PURL: https://purl.expasy.org/prosite/rule/PRU00583
        General rule information
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    | Accession | PRU00583 | 
| Dates | 12-SEP-2006 (Created) 21-NOV-2019 (Last updated, Version 6) | 
| Data class | Domain; | 
| Predictors | PROSITE; PS51253; HTH_CENPB | Name | CENPB-type HTH domain | 
| Function | The CENPB-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 70-75 amino acids, present in eukaryotic centromere proteins and transposases. | 
| Scope(s) | Eukaryota | 
| Example(s) | P07199 (CENPB_HUMAN); | 
        Propagated annotation
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        Comments
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    | SUBCELLULAR LOCATION | Nucleus. | 
    
    Keywords
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    Gene Ontology
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    | GO:0003677; Molecular function:DNA binding | 
| GO:0005634; Cellular component:nucleus | 
    
    Features
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    | From: PS51253 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH CENPB-type #" | |||||||||
| DNA_BIND | 34 | 64 | /note="H-T-H motif" | |||||||||
    
    Additional information
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    | Size range | 60-85 amino acids | 
| Related rules | None | 
| Fusion | None | 
| Repeats | 1-2 | 
| Topology | Not cytoplasmic | 
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UniProtKB rule member sequences
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    - UniProtKB/Swiss-Prot sets
 Eukaryota [31] All [ 31 ] 
 
- Retrieve set of proteins with 3D structure for this domain
