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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00601


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00601
General rule information [?]

Accession PRU00601
Dates 14-DEC-2011 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51266; ZF_CHY
Name Zinc finger CHY-type
Function Fill in
Scope(s) Eukaryota
Example(s) O14033;

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case (<Feature:PS51266:8=[CH]> and <Feature:PS51266:10=[CH]> and <Feature:PS51266:28=[CH]> and <Feature:PS51266:31=[CH]>) or (<Feature:PS51266:21=[CH]> and <Feature:PS51266:22=[CH]> and <Feature:PS51266:32=[CH]> and <Feature:PS51266:38=[CH]>) or (<Feature:PS51266:50=[CH]> and <Feature:PS51266:53=[CH]> and <Feature:PS51266:63=[CH]> and <Feature:PS51266:66=[CH]>)
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS51266
Key From To Description Tag Condition FTGroup
case <Feature:PS51266:8=[C]> and <Feature:PS51266:10=[H]> and <Feature:PS51266:28=[C]> and <Feature:PS51266:31=[C]> and <Feature:PS51266:21=[C]> and <Feature:PS51266:22=[C]> and <Feature:PS51266:32=[H]> and <Feature:PS51266:38=[H]> and <Feature:PS51266:50=[C]> and <Feature:PS51266:53=[C]> and <Feature:PS51266:63=[C]> and <Feature:PS51266:66=[C]>
ZN_FING from to /note="CHY-type #"
else case <Feature:PS51266:8=[CH]> and <Feature:PS51266:10=[CH]> and <Feature:PS51266:28=[CH]> and <Feature:PS51266:31=[CH]> and <Feature:PS51266:21=[CH]> and <Feature:PS51266:22=[CH]> and <Feature:PS51266:32=[CH]> and <Feature:PS51266:38=[CH]> and <Feature:PS51266:50=[CH]> and <Feature:PS51266:53=[CH]> and <Feature:PS51266:63=[CH]> and <Feature:PS51266:66=[CH]>
ZN_FING from to /note="CHY-type #; atypical"
else
ZN_FING from to /note="CHY-type #; degenerate"
end case
BINDING 8 8 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 21 21 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 22 22 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 31 31 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 32 32 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 38 38 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 50 50 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 53 53 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 63 63 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 66 66 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3

Additional information [?]

Size range 58-95 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]