We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00614
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00614
General rule information
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| Accession | PRU00614 |
| Dates | 11-JUL-2007 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51284; DOC |
Name | DOC domain |
| Function | The DOC domain is found in the APC10 subunit of a multi-subunit E3 protein ubiquitin ligase as well as in several hypothetical proteins that may mediate ubiquitination reactions, because they contain combinations of either RING finger, cullin or HECT domains. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9UM13; |
Propagated annotation
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Features
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| From: PS51284 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="DOC #" | |||||||||
Additional information
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| Size range | 175-190 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [27] All [ 27 ]
- Retrieve set of proteins with 3D structure for this domain