We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00615
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00615
General rule information
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| Accession | PRU00615 |
| Dates | 15-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50531; HTH_IS21 |
Name | IS21 transposase-type HTH domain |
| Function | The IS21 transposase-type HTH domain is a putative DNA-binding, helix-turn-helix (HTH) domain of about 60-65 amino acids, present in transposases of IS21-like prokaryotic insertion sequences. |
| Scope(s) |
Bacteria Archaea |
| Example(s) | P0A134; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
Features
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| From: PS50531 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH IS21-type #" | |||||||||
| DNA_BIND | 14 | 35 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 50-75 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [9] All [ 9 ]
- Retrieve set of proteins with 3D structure for this domain