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annotation rule: PRU00634

General rule information [?]

Accession PRU00634
Dates 4-JAN-2012 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51234; TSP3
Name Thrombospondin type-3 (TSP3) repeat
Function The calcium-binding TSP3 repeats are a tandem of aspartic acid-rich motifs, which resembles EF hands in the acidic side chains. But unlike EF hands, the calcium-binding loops of the TSP3 repeats are not flanked by secondary structure elements. The individual calcium-binding repeats are linked by disulfide bonds to each other.

Propagated annotation [?]


Gene Ontology [?]

GO:0005509; Molecular function: calcium ion binding.

Keywords [?]


Features [?]

From: PS51234
Key     From     To       Description   Tag   Condition   FTGroup
REPEAT     from     to       TSP type-3 #        

Additional information [?]

Size range 13-53 amino acids
Related rules None
Repeats 8
Topology Undefined
Example P35442 (TSP2_HUMAN)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]