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annotation rule: PRU00634

General rule information [?]

Accession PRU00634
Dates 4-JAN-2012 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51234; TSP3
Name Thrombospondin type-3 (TSP3) repeat
Function The calcium-binding TSP3 repeats are a tandem of aspartic acid-rich motifs, which resembles EF hands in the acidic side chains. But unlike EF hands, the calcium-binding loops of the TSP3 repeats are not flanked by secondary structure elements. The individual calcium-binding repeats are linked by disulfide bonds to each other.

Propagated annotation [?]

Gene Ontology [?]

GO:0005509; Molecular function: calcium ion binding.

Keywords [?]

Features [?]

From: PS51234
Key     From     To       Description   Tag   Condition   FTGroup
REPEAT     from     to       TSP type-3 #        

Additional information [?]

Size range 13-53 amino acids
Related rules None
Repeats 8
Topology Undefined
Example P35442 (TSP2_HUMAN)
Comments None


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UniProtKB rule member sequences [?]