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annotation rule: PRU00634 |
Accession | PRU00634 |
Dates | 4-JAN-2012 (Created) 21-NOV-2019 (Last updated, Version 3) |
Data class | Domain |
Predictors | PROSITE; PS51234; TSP3 |
Name | Thrombospondin type-3 (TSP3) repeat |
Function | The calcium-binding TSP3 repeats are a tandem of aspartic acid-rich motifs, which resembles EF hands in the acidic side chains. But unlike EF hands, the calcium-binding loops of the TSP3 repeats are not flanked by secondary structure elements. The individual calcium-binding repeats are linked by disulfide bonds to each other. |
From: PS51234 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REPEAT | from | to | TSP type-3 # |
Size range | 13-53 amino acids |
Related rules | None |
Repeats | 8 |
Topology | Undefined |
Example | P35442 (TSP2_HUMAN) |
Scope | Eukaryota |
Comments | None |
Eukaryota | [23] |