ProRule PRU00657
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PURL: https://purl.expasy.org/prosite/rule/PRU00657
        General rule information
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    | Accession | PRU00657 | 
| Dates | 17-APR-2008 (Created) 21-NOV-2019 (Last updated, Version 4) | 
| Data class | Domain; | 
| Predictors | PROSITE; PS51327; DICER_DSRBF | Name | Dicer double-stranded RNA-binding fold domain | 
| Function | A typical eukaryotic Dicer consists of a helicase domain, a domain of unknown function, and a PAZ domain at the amino (N)-terminus as well as two ribonuclease III domains and a dsRNA-binding domain (dsRBD) at the carboxy (C)-terminus. | 
| Scope(s) | Eukaryota | 
| Example(s) | Q9UPY3 (DICER_HUMAN); | 
        Propagated annotation
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        Comments
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    | case <AnyFeature:PS51192> and <AnyFeature:PS51194> | |
| SIMILARITY | Belongs to the helicase family. Dicer subfamily. | 
| end case | |
    
    Keywords
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    Gene Ontology
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    | GO:0003723; Molecular function:RNA binding | 
    
    Features
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    | From: PS51327 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Dicer dsRNA-binding fold #" | |||||||||
    
    Additional information
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    | Size range | 90-100 amino acids | 
| Related rules | None | 
| Fusion | None | 
| Repeats | 1 | 
| Topology | Undefined | 
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UniProtKB rule member sequences
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    - UniProtKB/Swiss-Prot sets
 Eukaryota [47] All [ 47 ] 
 
- Retrieve set of proteins with 3D structure for this domain
