ProRule PRU00657
General rule information
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| Accession | PRU00657 |
| Dates | 17-APR-2008 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51327; DICER_DSRBF |
Name | Dicer double-stranded RNA-binding fold domain |
| Function | A typical eukaryotic Dicer consists of a helicase domain, a domain of unknown function, and a PAZ domain at the amino (N)-terminus as well as two ribonuclease III domains and a dsRNA-binding domain (dsRBD) at the carboxy (C)-terminus. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9UPY3 (DICER_HUMAN); |
Propagated annotation
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Comments
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| case <AnyFeature:PS51192> and <AnyFeature:PS51194> | |
| SIMILARITY | Belongs to the helicase family. Dicer subfamily. |
| end case | |
Keywords
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Gene Ontology
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| GO:0003723; Molecular function:RNA binding |
Features
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| From: PS51327 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Dicer dsRNA-binding fold #" | |||||||||
Additional information
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| Size range | 90-100 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [45] All [ 45 ]
- Retrieve set of proteins with 3D structure for this domain