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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00657


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00657
General rule information [?]

Accession PRU00657
Dates 17-APR-2008 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51327; DICER_DSRBF
Name Dicer double-stranded RNA-binding fold domain
Function A typical eukaryotic Dicer consists of a helicase domain, a domain of unknown function, and a PAZ domain at the amino (N)-terminus as well as two ribonuclease III domains and a dsRNA-binding domain (dsRBD) at the carboxy (C)-terminus.
Scope(s) Eukaryota
Example(s) Q9UPY3;

Propagated annotation [?]

Comments [?]

case <AnyFeature:PS51192> and <AnyFeature:PS51194>
SIMILARITYBelongs to the helicase family. Dicer subfamily.
end case

Keywords [?]

RNA-binding

Gene Ontology [?]

GO:0003723; Molecular function:RNA binding

Features [?]

From: PS51327
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Dicer dsRNA-binding fold #"

Additional information [?]

Size range 90-100 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]