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ProRule PRU00657
General rule information
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Accession | PRU00657 |
Dates | 17-APR-2008 (Created)
21-NOV-2019 (Last updated, Version 3) |
Data class | Domain; |
Predictors |
PROSITE; PS51327; DICER_DSRBF |
Name | Dicer double-stranded RNA-binding fold domain |
Function | A typical eukaryotic Dicer consists of a helicase domain, a domain of unknown function, and a PAZ domain at the amino (N)-terminus as well as two ribonuclease III domains and a dsRNA-binding domain (dsRBD) at the carboxy (C)-terminus. |
Scope(s) |
Eukaryota |
Example(s) | Q9UPY3 (DICER_HUMAN); |
Propagated annotation
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Comments
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case <AnyFeature:PS51192> and <AnyFeature:PS51194> | |
SIMILARITY | Belongs to the helicase family. Dicer subfamily. |
end case |
Keywords
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Gene Ontology
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GO:0003723; Molecular function:RNA binding |
Features
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From: PS51327 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="Dicer dsRNA-binding fold #" |
Additional information
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Size range | 90-100 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [45] All [ 45 ]
- Retrieve set of proteins with 3D structure for this domain