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annotation rule: PRU00657

General rule information [?]

Accession PRU00657
Dates 17-APR-2008 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51327; DICER_DSRBF
Name Dicer double-stranded RNA-binding fold domain
Function A typical eukaryotic Dicer consists of a helicase domain, a domain of unknown function, and a PAZ domain at the amino (N)-terminus as well as two ribonuclease III domains and a dsRNA-binding domain (dsRBD) at the carboxy (C)-terminus.

Propagated annotation [?]


Comments [?]

case <AnyFeature:PS51192> and <AnyFeature:PS51194>
Similarity Belongs to the helicase family. Dicer subfamily.
end case


Gene Ontology [?]

GO:0003723; Molecular function: RNA binding.

Keywords [?]


Features [?]

From: PS51327
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Dicer dsRNA-binding fold #        

Additional information [?]

Size range 90-100 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9UPY3 (DICER_HUMAN)
Scope
Eukaryota

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]