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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00671


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00671
General rule information [?]

Accession PRU00671
Dates 30-NOV-2007 (Created)
19-NOV-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS51341; ZF_LTAG_D1
Name Zinc finger large T-antigen (T-ag) D1-type
Function Undefined
Scope(s) Viruses
Polyomaviridae
Example(s) P03070;

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case <Feature:PS51341:38=[CH]> and <Feature:PS51341:41=[CH]> and <Feature:PS51341:49=[CH]> and <Feature:PS51341:53=[CH]>
GO:0008270; Molecular function:zinc ion binding
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51341
Key From To Description Tag Condition FTGroup
case <Feature:PS51341:38=[C]> and <Feature:PS51341:41=[C]> and <Feature:PS51341:49=[H]> and <Feature:PS51341:53=[H]>
ZN_FING from to /note="T-ag D1-type #"
else case <Feature:PS51341:38=[CH]> and <Feature:PS51341:41=[CH]> and <Feature:PS51341:49=[CH]> and <Feature:PS51341:53=[CH]>
ZN_FING from to /note="T-ag D1-type #; atypical"
else
ZN_FING from to /note="T-ag D1-type #; degenerate"
end case
BINDING 38 38 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 41 41 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 49 49 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 53 53 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 90-100 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]