We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00676
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00676
General rule information
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| Accession | PRU00676 |
| Dates | 14-JAN-2008 (Created)
27-JUN-2022 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51344; HTH_TFE_IIE |
Name | TFE/IIEalpha-type HTH domain |
| Function | It has been proposed that the TFE/IIEalpha-type HTH domain acts as a bridging factor or adapter between the TATA box-binding protein, the polymerase, and possibly promoter DNA. |
| Scope(s) |
Eukaryota Archaea |
| Example(s) | P29083; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Features
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| From: PS51344 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH TFE/IIEalpha-type #" | |||||||||
Additional information
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| Size range | 85-110 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [52] Eukaryota [8] All [ 60 ]
- Retrieve set of proteins with 3D structure for this domain