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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00682


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00682
General rule information [?]

Accession PRU00682
Dates 15-APR-2008 (Created)
27-JUN-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51351; TFIIE_BETA_C
Name TFIIE beta central core DNA-binding domain
Function The ~120-residue central core domain of TFIIE beta plays a role in double-stranded DNA binding of TFIIE.
Scope(s) Eukaryota
Example(s) Q2KJF9;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.
SIMILARITYBelongs to the TFIIE beta subunit family.

Keywords [?]

DNA-binding
Nucleus
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS51351
Key From To Description Tag Condition FTGroup
DNA_BIND from to /note="TFIIE beta #"

Additional information [?]

Size range 70-85 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]