ProRule PRU00697

General rule information [?]

Accession PRU00697
Dates 15-APR-2016 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51364; TB
Name TGF-beta binding (TB) domain
Function The TB fold is globular with six beta-strands and two alpha-helices. The pairing of the eight cysteines is 1-3, 2-6, 4-7, and 5-8, creating a fairly rigid structure.
Scope(s) Eukaryota
Example(s) Q00918 (LTBP1_RAT);

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51364
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="TB #"
DISULFID 3 25 disulf C-x*-C
DISULFID 12 37 disulf C-x*-C
DISULFID 26 40 disulf C-x*-C
DISULFID 27 52 disulf C-x*-C

Additional information [?]

Size range 30-72 amino acids
Related rules None
Fusion None
Repeats 1-9
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]