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annotation rule: PRU00697

General rule information [?]

Accession PRU00697
Dates 15-APR-2016 (Created)
16-DEC-2016 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51364; TB
Name TGF-beta binding (TB) domain
Function The TB fold is globular with six beta-strands and two alpha-helices. The pairing of the eight cysteines is 1-3, 2-6, 4-7, and 5-8, creating a fairly rigid structure.

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS51364
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       TB #        
DISULFID     3     25           disulf   C-x*-C  
DISULFID     12     37           disulf   C-x*-C  
DISULFID     26     40           disulf   C-x*-C  
DISULFID     27     52           disulf   C-x*-C  

Additional information [?]

Size range 30-72 amino acids
Related rules None
Repeats 1-9
Topology Undefined
Example Q00918 (LTBP1_RAT)
Eukaryota; Euteleostomi
Comments None


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.

UniProtKB rule member sequences [?]