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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00697


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00697
General rule information [?]

Accession PRU00697
Dates 15-APR-2016 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51364; TB
Name TGF-beta binding (TB) domain
Function The TB fold is globular with six beta-strands and two alpha-helices. The pairing of the eight cysteines is 1-3, 2-6, 4-7, and 5-8, creating a fairly rigid structure.
Scope(s) Eukaryota
Euteleostomi
Example(s) Q00918;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51364
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="TB #"
DISULFID 3 25 disulf C-x*-C
DISULFID 12 37 disulf C-x*-C
DISULFID 26 40 disulf C-x*-C
DISULFID 27 52 disulf C-x*-C

Additional information [?]

Size range 30-72 amino acids
Related rules None
Fusion None
Repeats 1-9
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]