ProRule PRU00697
General rule information
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| Accession | PRU00697 |
| Dates | 15-APR-2016 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51364; TB |
Name | TGF-beta binding (TB) domain |
| Function | The TB fold is globular with six beta-strands and two alpha-helices. The pairing of the eight cysteines is 1-3, 2-6, 4-7, and 5-8, creating a fairly rigid structure. |
| Scope(s) |
Eukaryota Euteleostomi |
| Example(s) | Q00918 (LTBP1_RAT); |
Propagated annotation
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Keywords
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| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Features
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| From: PS51364 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="TB #" | |||||||||
| DISULFID | 3 | 25 | disulf | C-x*-C | ||||||||
| DISULFID | 12 | 37 | disulf | C-x*-C | ||||||||
| DISULFID | 26 | 40 | disulf | C-x*-C | ||||||||
| DISULFID | 27 | 52 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 30-72 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-9 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [33] All [ 33 ]
- Retrieve set of proteins with 3D structure for this domain