ProRule PRU00710
General rule information
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| Accession | PRU00710 |
| Dates | 22-MAY-2008 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51378; INVERT_DEFENSINS |
Name | Invertebrate defensins family |
| Function | Invertebrate defensins are a family of cysteine-rich antimicrobial peptides, primarily active against Gram-positive bacteria. |
| Scope(s) |
Eukaryota Fungi Metazoa |
| Example(s) | P91793 (DEFA_AEDAE); |
Propagated annotation
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Comments
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| FUNCTION | Antibacterial peptide mostly active against Gram-positive bacteria. |
| case <AnyFeature:Signal> | |
| SUBCELLULAR LOCATION | Secreted. |
| end case | |
| SIMILARITY | Belongs to the invertebrate defensin family. |
Keywords
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| Antibiotic | |
| Antimicrobial | |
| Defensin | |
| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Gene Ontology
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| GO:0006952; Biological process:defense response |
Features
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| From: PS51378 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DISULFID | 4 | 25 | disulf | C-x*-C | ||||||||
| DISULFID | 11 | 31 | disulf | C-x*-C | ||||||||
| DISULFID | 15 | 33 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 25-50 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [69] All [ 69 ]
- Retrieve set of proteins with 3D structure for this domain