We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00721
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00721
General rule information
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| Accession | PRU00721 |
| Dates | 31-JUL-2008 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51389; XIN |
Name | Xin repeat |
| Function | The Xin repeat is an actin-binding motif, capable of binding to actin filaments and organizing microfilaments into loose networks. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | Q5PZ43; |
Propagated annotation
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Comments
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| DOMAIN | Xin repeats bind F-actin. |
| SIMILARITY | Belongs to the Xin family. |
Keywords
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Gene Ontology
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| GO:0003779; Molecular function:actin binding |
Features
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| From: PS51389 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REPEAT | from | to | /note="Xin #" | |||||||||
Additional information
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| Size range | 15-20 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 17-28 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [7] All [ 7 ]
- Retrieve set of proteins with 3D structure for this domain