ProRule PRU00726

General rule information [?]

PURL	https://purl.expasy.org/prosite/rule/PRU00726
Accession	PRU00726
Dates	11-JUL-2008 (Created) 19-NOV-2022 (Last updated, Version 12)
Data class	Domain;
Predictors	PROSITE; PS51393; LIPOXYGENASE_3
Name	Lipoxygenase iron-binding catalytic domain
Function	Lipoxygenases (EC 1.13.11.-) form a class of iron-containing fatty acid dioxygenases, which catalyze the hydroperoxidation of lipids, containing a cis,cis-1,4-pentadiene structure.
Scope(s)	Eukaryota Bacteria
Example(s)	Q84YK8 (LOXC2_ORYSJ); Q9BYJ1 (LOXE3_HUMAN); Q8RNT4 (LOX_PSEAI);

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Viridiplantae>
Protein name	AltName: Full=lipoxygenase; EC=1.13.11.-;

Comments [?]

FUNCTION	Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.
end case

Keywords [?]

Gene Ontology [?]

GO:0016702; Molecular function:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
case <FTGroup:1>
GO:0005506; Molecular function:iron ion binding
GO:0046872; Molecular function:metal ion binding
end case
GO:0016491; Molecular function:oxidoreductase activity
case <OCellular component:Viridiplantae>
GO:0006633; Biological process:fatty acid biosynthetic process
GO:0008610; Biological process:lipid biosynthetic process
GO:0031408; Biological process:oxylipin biosynthetic process
end case
case <OCellular component:Bacteria>
GO:0042597; Cellular component:periplasmic space
end case

Cross-references [?]

PROSITE	PS00711; LIPOXYGENASE_1; 1;
PROSITE	PS00081; LIPOXYGENASE_2; 1;

Features [?]

From: PS51393

Key

From

Description

Tag

Condition

FTGroup

DOMAIN

from

/note="Lipoxygenase #"

BINDING

340