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annotation rule: PRU00745

General rule information [?]

Accession PRU00745
Dates 28-NOV-2008 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51412; MACPF_2
Name Membrane attack complex/perforin (MACPF) domain
Function The MACPF domain oligomerizes, undergoes conformational change, and is required for lytic activity.

Propagated annotation [?]


Cross-references [?]

PROSITE PS00279; MACPF_1; 1;

Features [?]

From: PS51412
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       MACPF #        

Additional information [?]

Size range 315-385 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example Q29RU4 (CO6_BOVIN)
Scope
Eukaryota
Bacteria
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]