ProRule PRU00745

General rule information [?]

Accession PRU00745
Dates 28-NOV-2008 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51412; MACPF_2
Name Membrane attack complex/perforin (MACPF) domain
Function The MACPF domain oligomerizes, undergoes conformational change, and is required for lytic activity.
Scope(s) Eukaryota
Example(s) Q29RU4 (CO6_BOVIN);

Propagated annotation [?]

Cross-references [?]

PROSITE PS00279; MACPF_1; 1;

Features [?]

From: PS51412
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="MACPF #"

Additional information [?]

Size range 315-385 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic


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UniProtKB rule member sequences [?]