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| annotation rule: PRU00745 |
General rule information
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| Accession | PRU00745 |
| Dates | 28-NOV-2008 (Created) 21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain |
| Predictors | PROSITE; PS51412; MACPF_2 |
| Name | Membrane attack complex/perforin (MACPF) domain |
| Function | The MACPF domain oligomerizes, undergoes conformational change, and is required for lytic activity. |
Propagated annotation
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Cross-references
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| PROSITE | PS00279; MACPF_1; 1; |
Features
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| From: PS51412 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | MACPF # | |||||||||
Additional information
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| Size range | 315-385 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
| Example | Q29RU4 (CO6_BOVIN) |
| Scope | Eukaryota
Bacteria |
| Comments | None |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [55]
- Retrieve set of proteins with 3D structure for this domain