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annotation rule: PRU00746

General rule information [?]

Accession PRU00746
Dates 12-DEC-2008 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain
Predictors PROSITE; PS51413; DBINO
Name DBINO domain
Function The DBINO (DNA binding domain of INO80) domain is characteristic of the INO80 subfamily and is predicted to have DNA-binding function.

Propagated annotation [?]


Comments [?]

Function ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subunit Component of the INO80 chromatin-remodeling complex.
Subcellular location Nucleus.

Gene Ontology [?]

GO:0006325; Biological process: chromatin organization.
GO:0006974; Biological process: cellular response to DNA damage stimulus.
GO:0006281; Biological process: DNA repair.
GO:0003677; Molecular function: DNA binding.
GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:0006351; Biological process: transcription, DNA-templated.

Keywords [?]

Activator
DNA damage
DNA repair
DNA-binding
Nucleus
Transcription
Transcription regulation

Features [?]

From: PS51413
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       DBINO #        

Additional information [?]

Size range 125-135 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example O14148 (INO80_SCHPO)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]