PRU00746

Accession	PRU00746
Dates	12-DEC-2008 (Created) 13-FEB-2023 (Last updated, Version 9)

Data class

Domain

Predictors

PROSITE; PS51413; DBINO

Name	DBINO domain

Function

The DBINO (DNA binding domain of INO80) domain is characteristic of the INO80 subfamily and is predicted to have DNA-binding function.

Function	ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subunit	Component of the INO80 chromatin-remodeling complex.
Subcellular location	Nucleus.

GO:0006325; Biological process: chromatin organization.
GO:0006974; Biological process: DNA damage response.
GO:0006281; Biological process: DNA repair.
GO:0003677; Molecular function: DNA binding.
GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.

Activator
DNA damage
DNA repair
DNA-binding
Nucleus
Transcription
Transcription regulation

From: PS51413

Key

From

To

Description

Tag

Condition

FTGroup

DOMAIN

from

to

DBINO #

Size range	125-135 amino acids
Related rules	None
Repeats	1
Topology	Not cytoplasmic
Example	O14148 (INO80_SCHPO)
Scope	Eukaryota
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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• UniProtKB/Swiss-Prot sets
  

  Eukaryota

  [30]

  
  
• Retrieve set of proteins with 3D structure for this domain