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ProRule PRU00746


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PURL: https://purl.expasy.org/prosite/rule/PRU00746
General rule information [?]

Accession PRU00746
Dates 12-DEC-2008 (Created)
13-FEB-2023 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS51413; DBINO
Name DBINO domain
Function The DBINO (DNA binding domain of INO80) domain is characteristic of the INO80 subfamily and is predicted to have DNA-binding function.
Scope(s) Eukaryota
Example(s) O14148;

Propagated annotation [?]

Comments [?]

FUNCTIONATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
SUBUNITComponent of the INO80 chromatin-remodeling complex.
SUBCELLULAR LOCATIONNucleus.

Keywords [?]

Activator
DNA damage
DNA repair
DNA-binding
Nucleus
Transcription
Transcription regulation

Gene Ontology [?]

GO:0006325; Biological process:chromatin organization
GO:0006974; Biological process:DNA damage response
GO:0006281; Biological process:DNA repair
GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS51413
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="DBINO #"

Additional information [?]

Size range 125-135 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]