ProRule PRU00752
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00752
General rule information
[?]
| Accession | PRU00752 |
| Dates | 11-FEB-2025 (Created)
11-FEB-2025 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51418; RAN |
Name | Small GTPase Ran-type domain |
| Function | GTP-binding proteins involved in nucleocytoplasmic transport. Required for the import of proteins into the nucleus and also for RNA export. |
| Scope(s) |
Eukaryota |
| Example(s) | P38545 (RAN_PLAFA); |
Propagated annotation
[?]
Comments
[?]
| SIMILARITY | Belongs to the small GTPase superfamily. Ran family. |
Keywords
[?]
Gene Ontology
[?]
| GO:0003924; Molecular function:GTPase activity |
| GO:0005525; Molecular function:GTP binding |
| GO:0005634; Cellular component:nucleus |
| GO:0006606; Biological process:protein import into nucleus |
| GO:0000054; Biological process:ribosomal subunit export from nucleus |
| GO:0005737; Cellular component:cytoplasm |
Features
[?]
| From: PS51418 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Small GTPase Ran-type #" | |||||||||
| REGION | 31 | 39 | /note="Switch-I #" | |||||||||
| REGION | 62 | 78 | /note="Switch-II #" | |||||||||
Additional information
[?]
| Size range | 162-182 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Eukaryota [51] All [ 51 ]
- Retrieve set of proteins with 3D structure for this domain