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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00757


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00757
General rule information [?]

Accession PRU00757
Dates 05-MAY-2020 (Created)
30-SEP-2022 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51423; MIRO
Name Miro domain
Function Small GTPase domain found in mitochondrial proteins involved in mitochondrial trafficking.
Scope(s) Eukaryota
Example(s) Q6CY37;

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=3.6.5.-;

Comments [?]

SIMILARITYBelongs to the mitochondrial Rho GTPase family.

Keywords [?]

GTP-binding
Hydrolase
Membrane
Mitochondrion
Mitochondrion outer membrane
Nucleotide-binding

Gene Ontology [?]

GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
GO:0007005; Biological process:mitochondrion organization
GO:0010821; Biological process:regulation of mitochondrion organization
GO:0007266; Biological process:Rho protein signal transduction

Features [?]

From: PS51423
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Miro #"

Additional information [?]

Size range 160-225 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]