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PROSITE entry PS51423


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General information about the entry

Entry name [info] MIRO
Accession [info] PS51423
Entry type [info] MATRIX
Date [info] 01-DEC-2008 CREATED;
12-AUG-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51417
Associated ProRule [info] PRU00757

Name and characterization of the entry

Description [info] Miro domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=170;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=165;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6404622; R2=0.0077605; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=4170; N_SCORE=35.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=498; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-32; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='R';  M= -66, -81, -63, -52, -73, -75, -55, -74,  37, -28,  21, -20,  17, -43,  99, -43, -63, -72, -76, -63;
/M: SY='N';  M= -10, -24,   8,  -1, -77, -59, -53, -76,  56, -78, -68,  75, -67, -47,   4,  28,   9, -72, -84, -69;
/M: SY='V';  M= -24, -24,  33, -27, -62, -74, -71,  -5, -64, -35, -51,   9, -12, -66, -19, -13,   7,  77, -88, -65;
/M: SY='F';  M= -63, -70, -85, -80,  75, -85, -74,  39, -77,   6, -16, -78, -81, -79, -76, -71, -58,  63, -61,   6;
/M: SY='R';  M= -65, -77, -61, -53, -66, -73, -53, -64,   9,  27,   0,  39, -75,  39,  85, -60, -61, -65, -76, -61;
/M: SY='C';  M= -60, 123, -82, -81, -61, -12, -83,  60, -77, -50, -52, -70, -82, -80, -82, -66, -59,  25, -87, -69;
/M: SY='F';  M= -35,  25, -72, -69,  51, -77,  36, -13,  12,  15, -47,   9, -78, -66, -37, -65, -59,  45, -63,  46;
/M: SY='V';  M= -56, -68, -84, -78, -50, -85, -81,  30, -76,  30, -11, -79, -79, -75, -76, -69, -54,  87, -82, -59;
/M: SY='C';  M= -22,  80, -83, -79,  32, -82, -77,  38, -77,  38, -42, -76, -82, -77, -78, -69, -58,  48, -74, -54;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='D';  M=  44, -74,  74,  25, -81, -61, -60, -73,  -4, -74, -11, -50,  47, -53, -61,  -4, -55, -37, -85, -71;
/M: SY='K';  M=   5, -37,   7,  43, -80, -45,  -9, -78,  52, -77, -68,   0,  41,  -9,  33,  -8, -22, -73, -79, -69;
/M: SY='G';  M=  -7, -24,   0, -61, -81,  80, -62, -82,  -3, -80, -15,  34, -68,  25, -26, -15, -61, -78, -77, -73;
/M: SY='V';  M=  22,  63, -70, -67, -64, -66, -73, -42, -66, -55, -55, -61, -72, -65, -70,  48,  29,  65, -86, -66;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='S';  M= -45, -63, -56, -58, -71, -56, -62, -67, -57, -71, -66, -45, -62, -53, -63,  88,  76, -59, -85, -66;
/M: SY='S';  M=  40, -64, -30, -59, -74,  11, -63, -68, -60, -72, -67, -49, -65, -54, -65,  84,  19, -23, -81, -68;
/M: SY='L';  M= -68, -70, -85, -78,  54, -85, -69,  11, -78,  76,   2, -81, -83, -74, -75, -76, -63,  -8, -64, -45;
/M: SY='I';  M= -65,  15, -85, -80, -45, -87, -75,  73, -78,  63,  15, -79, -79, -73, -78, -75, -61,  -9, -73, -55;
/M: SY='M';  M= -11, -72,  20,  15, -70, -66, -55, -60, -48, -18,  55,  37, -68,  51,  34,   2,  21,  -8, -81, -63;
/M: SY='S';  M=  53,  34, -60, -59, -74, -17, -63, -69, -59, -72, -66, -14, -66, -12, -64,  79,  -5, -39, -81, -69;
/M: SY='F';  M= -17, -70, -85, -79,  92, -82, -68, -40, -77,  57,   4, -79, -84, -78, -75, -73, -64, -24, -54, -34;
/M: SY='L';  M=   9, -69, -82, -76, -49, -80, -76,  43, -75,  57, -36, -77, -78, -72, -76, -67, -28,  51, -76, -58;
/M: SY='G';  M= -32, -74, -56, -19, -78,  66, -10, -77,  41, -78, -69,  28, -67,   3, -14,  24, -27, -26, -77, -70;
/M: SY='R';  M= -39, -80,  36,  55, -80,  -3,   1, -83,   7, -77, -69,  14, -67, -18,  75, -56, -61, -77, -81, -67;
/M: SY='S';  M= -22, -72,  -1,  39, -77,   8, -59, -71, -23, -53, -67,  22,  26,  21, -22,  53,  21, -26, -82, -69;
/M: SY='F';  M= -71, -72, -81, -78,  96, -80, -62, -24, -74,  22,  36, -24, -82, -76, -72, -71, -15, -51,  35,  52;
/M: SY='P';  M=  -9, -72,  -9, -20, -67,  -7,  25,  12, -27, -59,  24, -23,  47, -25, -65,  44, -12,  31, -80, -28;
/M: SY='E';  M= -20, -76,  49,  51, -79, -21,  11, -77, -12, -76, -69,  14,  40, -49,  20, -30,  39, -72, -85, -69;
/M: SY='N';  M=  14, -71,  -4,  23, -69, -31, -57,  -9, -32,   7, -57,  60, -23,  43, -59,   2,   7, -22,   8, -65;
/M: SY='Y';  M= -25, -74,  -8, -26, -48, -76, -59,  31,  14, -15, -49, -64, -73,  16,   6, -29,  -2,  40, -62,  70;
/M: SY='P';  M= -46, -80,   1,   5, -77, -15,  27, -13,  -3, -73, -64,  13,  72,  63,  -6,   5, -13, -71, -78, -22;
/I:         I=-25; MD=-63;
/M: SY='P';  M= -10, -80,   9, -54, -78, -24, -12,  10,  31, -60, -65,  13,  72,   9,  15,  14, -57, -66, -81, -71; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='R';  M= -36, -89, -83,  -3, -80, -94, -81, -36, -63, -22,  -6, -80, -89, -71,  54, -76,   7,  36, -97, -79; D=-25;
/I:         I=-25; DM=-63;
/M: SY='L';  M=  11, -84, -10, -29,   6, -40,   7, -34, -80,  40, -57, -40,  33, -77, -83, -75, -72, -25, -85, -68; D=-25;
/I:         I=-25; DM=-63;
/M: SY='P';  M= -62, -81,  16,  48, -83, -29, -65, -77,  -6, -79, -72, -58,  78, -19, -64, -17,  49, -73, -85, -76; D=-25;
/I:         I=-25; DM=-63;
/M: SY='P';  M= -29, -82, -25,  43, -72, -75,  43,  30, -23, -66, -61, -61,  59,  30,   1, -60,  15, -60, -79,  -5; D=-25;
/I:         I=-25; DM=-63;
/M: SY='I';  M= -66, -79, -24, -64,  -1, -80, -68,  55,  31, -40, -52,  -8,  22,  -5,  13, -65, -17,  21, -72,  22; D=-25;
/I:         I=-25; DM=-63;
/M: SY='T';  M=   4, -67, -61, -24, -69, -64, -66, -56, -31, -21,  -3,  -9,  53, -59, -66,  36,  71,   9, -83, -67;
/M: SY='I';  M= -34, -74, -77, -72, -27, -53, -71,  72, -26,  13,   3, -70, -36, -66,  26, -66,  -1,  26, -70,  19;
/M: SY='P';  M= -62, -80, -60, -59, -60, -66,  17, -17, -60, -69, -61,  42,  91, -25, -39,  11, -14, -13, -68,  57;
/M: SY='A';  M=  63,  15, -66, -60, -72, -18, -66, -33,  -2, -65,  -4, -24,  23, -57,  24,  10,  -8,   8, -79, -69;
/M: SY='D';  M= -59, -73,  56,  23, -65, -39, -65,  44, -61, -54, -54,  33, -70, -60, -68, -19, -12,  50, -87, -65;
/M: SY='N';  M= -35, -70,  31, -59,  48, -65, -58,   5, -13, -59, -58,  77, -21, -61, -32, -12, -35,  31, -76, -54;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='T';  M= -35, -65, -55,   1,  14, -62, -61, -61, -57, -64,  -2,  25, -64, -12, -63,  53,  79, -21, -78, -16;
/M: SY='P';  M= -41, -74, -70, -64,   6, -72, -71, -22, -20, -15, -54,   6,  83, -67, -70,  -5, -28,  59, -79, -64;
/M: SY='E';  M= -59, -79,  40,  81, -74, -16, -53, -79,  -9, -54, -69, -51, -62,  35,   3,  11, -58, -75, -75,  17;
/I:         I=-8; MD=-20;
/M: SY='V';  M= -82, -96, -98, -35, -81, -55, -96, -35, -91,  -1,  15, -96,   3, -21, -45, -44, -80,  45,-105, -86; D=-8;
/I:         I=-8; MD=-20;
/M: SY='Y';  M= -28,  15, -86, -35, -78, -42, -80, -41, -22, -92, -86,   1,  -1, -33, -86,  -7,  -7, -88, -86,  51; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='G';  M= -78,-101, -15, -95, -95,  65, -90,-104, -93, -41, -93, -35, -95, -90, -99, -41, -90,-102, -95,  -3; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Q';  M=  -7, -90, -72, -18, -94, -80, -73, -42,  40, -86, -78, -22, -81,  62, -59,  12, -11, -39, -93, -81; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Q';  M= -41, -79,  10,  51, -77, -38, -54, -26,  16, -73, -65,  34,  36,  63,  12, -17, -57, -37, -77, -16;
/M: SY='K';  M= -61,  61, -65, -31, -29, -75, -65,  10,  71, -37, -55, -22, -72, -24,  -2, -61, -23,  38, -73,  14;
/M: SY='Y';  M= -63, -76, -63, -64, -41, -69,  15, -32, -61, -62, -57,  16,  54, -60, -64,  12,  38, -40, -50, 100;
/M: SY='T';  M= -27, -66, -72, -70, -50, -77, -68, -18, -69,  68,  -4, -66, -73, -67, -71, -56,  72, -24, -77, -58;
/M: SY='I';  M= -59, -71, -73, -71, -55, -79,  42,  67, -40,   4, -43, -64, -72, -66, -19,   5,  34,  41, -80, -57;
/M: SY='L';  M= -65, -71, -85, -79, -44, -87, -73,  61, -77,  69,  32, -80, -80, -72, -77, -75, -61,   8, -73, -55;
/M: SY='V';  M= -58,  35, -14,  11, -34, -76,  38,  24, -25, -53, -52, -61, -73,  36,  28,  -4, -56,  57, -82, -60;
/M: SY='D';  M= -64, -81,  93,  81, -86, -69, -53, -85, -48, -81, -78, -44, -61, -43, -57, -56, -59, -80, -91, -72;
/M: SY='T';  M= -60, -68, -73, -72,  30, -79, -67,  29, -69,  19, -45, -65, -73, -70, -71, -56,  67,  37, -65,  46;
/M: SY='S';  M= -29, -72,  31, -56, -17,  46, -62, -72, -36, -51, -68, -12,  19,   6, -25,  66, -50, -23, -79, -67;
/M: SY='E';  M=  16, -72,  10,  59, -28, -13, -61,  -6, -54, -67, -63,   7, -27,  -2, -61,  44, -30,  10, -80, -67;
/M: SY='D';  M= -14, -73,  51,   8, -71, -65, -57, -64,  10,   8, -60, -13, -68,  24,  34,  41, -18, -15, -82, -65;
/I:         I=-31; MD=-79;
/M: SY='E';  M= -71, -92,  -5,  59, -86,  -5, -70, -41, -64, -88, -82, -25,  41, -60, -28,  15, -69, -85, -87,   8; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='Q';  M=   3, -93,  -5,  22, -94, -81,  10, -90, -29, -56, -79,   6,  11,  58, -35, -30, -44, -87, -95, -40; D=-31;
/I:         I=-31; DM=-79;
/M: SY='D';  M=  18, -83,  51,  28, -85, -16, -17, -27, -29, -40, -75, -11,   2, -62, -71,  -6,   4, -74, -94, -78; D=-31;
/I:         I=-31; DM=-79;
/M: SY='R';  M= -33, -80,   3,   4,  -1, -81, -68,  29,  17,  14,  -7, -66, -27,  -3,  36, -67,  -8,  -1, -79, -63; D=-31;
/I:         I=-31; DM=-79;
/M: SY='E';  M= -17, -73,  32,  52, -18, -29, -61,   8, -59,  40,  -1,  12, -28, -25, -64, -28,  -6, -54, -78, -62;
/M: SY='W';  M=   9, -74, -57,  28,  28, -44,  15, -34,  -3,  -5, -58,  26,  20,  25,  -2, -10,  12, -50,  32, -11;
/M: SY='L';  M= -43, -69, -21, -33, -53, -71, -61, -11, -64,  62,  10,  55, -76,  -5, -67,  -9,  11,  -7, -78, -59;
/M: SY='Q';  M=  29, -72, -28, -30, -72, -16,  26, -17,  35, -46, -59,  -8,  -8,  51,   7, -10,  24,  -9, -77, -26;
/M: SY='E';  M=  20, -74, -11,  54, -77, -35,   3, -74,  40, -56,   4, -53,   6,   2,   9,  35, -32, -68, -78, -67;
/M: SY='E';  M=  14, -75, -46,  76, -74, -25, -58, -71,  16,   3, -62, -56, -63,   4,  13,  21, -56, -66, -77, -68;
/M: SY='L';  M= -65, -74,  31,  21, -18, -82, -68,  53, -17,  54,  -7, -67, -74, -63, -68, -69, -60,  -7, -75, -57;
/M: SY='R';  M=  30, -71,  33, -11, -74, -64, -18, -38,  31, -47, -21, -12, -67, -35,  49,  18,  18, -17, -81, -65;
/M: SY='Q';  M=  31, -72, -55,   8, -76, -62, -57, -22,  47, -58,  -3,  25, -32,  54,  14,   7,  10, -63, -77, -66;
/M: SY='C';  M=  69, 123, -73, -69, -73, -60, -74, -71, -69, -68, -65, -64, -77, -69, -74, -15, -55, -59, -86, -76;
/M: SY='D';  M= -66, -78, 107, -36, -84, -61,  21, -84, -53, -83, -79,  60, -68, -53, -61, -44, -55, -82,-102, -69;
/M: SY='V';  M=   2, -66, -82, -76, -54, -80, -83,  14, -74,  -4, -42, -77, -78, -75, -76, -65, -52,  93, -85, -61;
/M: SY='I';  M=  35, -70, -81, -76, -54, -77, -81,  79, -74,  -6, -41, -74, -74, -72, -77, -63, -55,  49, -77, -60;
/M: SY='C';  M= -25, 129, -83, -79, -60, -77, -82,  -7, -76,  -9, -57, -73, -85, -79, -80, -66, -61,  34,  83, -64;
/M: SY='L';  M= -66, -71, -83, -78,  33, -85, -66,  21, -76,  69, -34, -80, -83, -72, -74, -74, -62,  17, -60,  47;
/M: SY='V';  M=  -7, -18, -77, -73, -55, -78, -76,  -2, -70,   4,  46, -71, -74, -71, -73, -60,  37,  80, -84, -61;
/M: SY='Y';  M= -72, -81, -71, -74,  32, -78,   6, -56, -66, -52, -50, -71, -83, -62, -63, -67, -66, -61, -29, 129;
/M: SY='D';  M=  19,  -9,  98, -40, -82, -58, -57, -79, -57, -80, -76, -40, -66, -54, -64,  50, -50, -73, -93, -70;
/I:         I=-42; MD=-106;
/M: SY='S';  M= -58,  46, -77, -76, -16, -35, -79,   3, -75, -47, -63, -67, -81, -71, -78,  65, -54,  46, -90, -71; D=-42;
/I:         I=-42; MI=-106; MD=-106; IM=-106; DM=-106;
/M: SY='S';  M= -36, -75,  34, -60, -84, -61, -66, -82, -64, -86, -80,  17, -73, -59, -70,  83,  10, -76, -95, -76; D=-42;
/I:         I=-42; DM=-106;
/M: SY='D';  M= -43, -77,  99,  -2, -84, -62, -51, -83, -39, -82, -77,  54, -68,  -4,  15, -13, -55, -80, -95, -70;
/M: SY='P';  M= -64, -83,  -4,  32, -17, -70,  64, -71,  -7, -46, -65, -18,  96, -55, -62, -38,  -3, -37, -81, -65;
/M: SY='Y';  M= -34, -77,  56,  40, -63, -48, -13, -75,  19, -73, -67,  29, -67,   4,   8,  15, -19, -73, -69,  56;
/M: SY='S';  M= -43, -63, -56, -58, -72, -53, -61, -70, -57, -73, -68, -45, -62, -51, -62,  97,  58, -62, -84, -66;
/M: SY='F';  M= -72,  -5, -85, -81,  97, -82, -64,   5, -76,   6, -48, -78, -84, -79, -74, -73, -66, -12,  68,  60;
/M: SY='E';  M=   9, -74,  48,  67, -79, -63, -56, -74,   4, -73,   4,   9, -63, -14, -21,  38, -52, -34, -83, -69;
/M: SY='Y';  M= -67, -80, -65, -59,  26, -47,  40, -68,  21, -39, -56, -60, -76, -23,  73, -22, -64, -68, -52,  84;
/M: SY='C';  M=  -3,  83, -83, -79, -54, -82, -81,  73, -76,  15, -42, -74, -78, -75, -79, -67, -57,  38, -80, -62;
/M: SY='A';  M=  53, -67, -29, -13, -72, -43, -65, -59, -55, -48, -61, -56,   5,  -4,  20,  47,  15,  18, -80, -67;
/M: SY='S';  M= -40, -71,  -7,  30, -67, -39, -58, -12,  -6,  11,   6,  37, -67,   0,  14,  40,  32, -59, -81, -64;
/M: SY='Y';  M= -66, -74, -76, -70,  33, -82,  26,  45,  20,  35,   2, -70, -77, -64, -25, -69, -61,  10, -59,  57;
/M: SY='W';  M= -72, -87, -84, -73,   4, -77, -66, -40, -60,   7, -57, -80, -80, -64,  36, -74, -74, -46, 144,  73;
/M: SY='M';  M= -23, -73, -23, -31, -58, -73, -61,  31,  41,  35,  57,  17, -71,  28, -26, -33, -33, -22, -75, -59;
/M: SY='P';  M= -64, -84, -58,  10, -80, -70, -17, -38,  42, -48,   5, -30,  88,  60,   9, -59, -60, -73, -76, -69;
/M: SY='Y';  M= -67, -75, -68, -13,  -9, -78,  74, -48, -66,  37,  24, -33, -78, -60, -64, -66, -30,   1, -53,  91;
/M: SY='F';  M=  -5, -75, -42, -41,  74, -44, -63,  22, -18, -19, -51, -70,  39, -33, -69, -29, -39,   0, -54,  53;
/M: SY='R';  M= -25, -76, -27, -56, -63, -70,  48, -39, -42, -19,  69,  42, -73,  15,  74, -58, -24, -38, -76,  11;
/M: SY='Q';  M= -39, -75,  46,  12, -67, -12, -56, -30, -51,  21, -17, -18, -69,  47,  28,  39, -55, -63, -77, -10;
/I:         I=-14; MD=-36;
/M: SY='L';  M= -20, -73,   3,  -5, -64,  21, -62, -59,   3,  41,  -6, -35, -71,  33, -11,  31, -14, -60, -77, -64; D=-14;
/I:         I=-14; MD=-36;
/M: SY='G';  M= -40,  -1, -36,  22, -21,  37, -88, -97, -36, -39, -89, -79, -91, -79, -24, -77,  -4, -93, -99, -90; D=-14;
/I:         I=-14; MD=-36;
/M: SY='V';  M= -34, -99,  -4, -13, -90, -13, -98, -18, -68, -25, -79, -24,-100, -91, -71, -88, -68,  33,-111, -93; D=-14;
/I:         I=-14; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='N';  M= -43, -75, -13,  35, -78, -19,   2, -76,  42, -76, -66,  67, -67,  33,  44, -23, -28, -38, -81, -67;
/M: SY='I';  M= -33, -69, -76, -73, -17, -80, -75,  57, -29,  34,   3, -69, -73, -69, -72, -22,  41,  40, -77, -57;
/M: SY='P';  M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83;
/M: SY='C';  M= -23, 102, -79, -77, -58, -77, -79,  57, -74, -18, -15, -69, -79, -74, -78,  13, -55,  45, -85, -65;
/M: SY='V';  M= -60, -71, -84, -79, -49, -86, -80,  67, -77,  32,  16, -78, -78, -74, -78, -71, -56,  67, -78, -57;
/M: SY='F';  M= -67, -71, -85, -79,  72, -84, -68,  24, -76,  52,  44, -78, -82, -75, -74, -74, -62,  16, -58,  12;
/M: SY='C';  M=  -3,  80, -81, -77, -57, -80, -83,  34, -74, -31, -46, -74, -79, -76, -77, -63, -16,  80, -86, -64;
/M: SY='A';  M=  67, -24, -64, -28, -78,  58, -67, -75, -15, -74, -67, -56, -67, -58,   8,   4, -57, -64, -76, -72;
/M: SY='N';  M=  17,  32, -52, -62, -65, -58, -55, -62, -57,  11, -58,  84, -71, -57, -63,  19,  44, -60, -83,  -6;
/M: SY='K';  M= -62, -77, -54, -11, -78, -70, -58, -77, 108, -77, -65, -48, -63, -40, -25, -57, -57, -40, -73, -66;
/M: SY='S';  M=  45,  52,  -1, -62, -25, -59, -65,  -3, -63,  -9, -58,  -3, -70, -60, -68,  58,  -8,  -2, -79, -28;
/M: SY='D';  M= -67, -80, 115,   8, -87, -64, -53, -86, -54, -84, -82,   4, -66, -53, -62, -55, -57, -82,-101, -71;
/M: SY='L';  M= -65, -71,  13, -65, -20, -30, -62, -42, -41,  73,  15,  23, -79,  -4,  -4, -37, -60, -48, -74, -56;
/M: SY='D';  M= -35, -77,  71,  -1, -28, -30,  31, -12, -18, -40, -62,  -1,  20, -20,  25, -58, -16,  17, -84, -18;
/M: SY='E';  M= -12, -27,  35,  61, -76, -19, -58, -45,  18, -25, -38,  -2,  27, -47,  10,  10, -27, -42, -81, -70;
/M: SY='Q';  M=  11, -72,  19,  -2, -23,  24, -33, -63, -28, -67, -62,  34, -69,  43, -12,  -7,  15,  12, -73,  25;
/M: SY='Q';  M= -59, -75,   1, -52, -31, -21,  -1, -66,  15, -54, -62,  38,  19,  53,  25,  25,  -2,  -4,  16,  24;
/M: SY='Q';  M= -19, -17, -55, -48, -75, -63,   9, -28, -25, -45,  -3,  43, -39,  93, -51,  27,  21, -10, -80, -63;
/M: SY='R';  M= -13, -76,  11,  18, -71, -34,  23, -59, -45, -52,  50,  -2,  22,  10,  61,  19,  -4, -45, -79, -22;
/M: SY='C';  M=  -1,  48, -18,  10,   2, -67,  47, -10, -20, -25, -58,  43,  20, -57, -27,  -1, -38, -17,  35,  39;
/M: SY='Q';  M=   0, -73,   7,  38, -75,  12,  13, -43, -32, -12, -62,  30, -24,  52, -23,  30, -10, -55, -80, -66;
/M: SY='V';  M= -40, -72, -30,   5, -29, -46,  -5,  40,  -8,  27,  37,   7, -13, -62, -66, -32, -23,  41, -77, -32;
/M: SY='Q';  M= -41, -73, -58,  17, -28, -65, -59,   0, -54,  13, -54,  -3,   5,  73, -58,  54, -30,  -4, -77, -62;
/I:         I=-10; MD=-25;
/M: SY='P';  M= -21, -83,  -2,  20, -81, -43, -63, -71, -56, -49, -15,  -5, 100,  28, -29, -57,   8, -42, -81, -75; D=-10;
/I:         I=-10; MD=-25;
/M: SY='D';  M=   8, -80,  60,  14, -78, -46,  28,  15, -59, -49, -68,  11, -73, -23,   9,   1, -19, -38, -91, -70; D=-10;
/I:         I=-10; MD=-25;
/M: SY='E';  M= -70, -87,  15,  76, -89, -51, -66, -42, -59, -81,  13,   8, -71, -25, -67,  -7,   9, -79, -94, -81; D=-10;
/I:         I=-10; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='I';  M= -56,-101,-110,-106, -17,-110,-106,  55,-104,  -3, -66,-102,-104,-100,-106, -25, -84,   0,-100, -82; D=-10;
/I:         I=-10; DM=-25;
/M: SY='M';  M= -67, -72, -82, -76,  76, -80, -58,  -5, -69,   8,  97, -74, -79, -68, -19, -71, -63,  -9, -52,  55;
/M: SY='C';  M=  -1, 102, -60,  -2,  -9, -67, -64, -69,   3, -67,  11,  29, -72, -19,   1,   5,  47, -62, -84, -67;
/M: SY='Q';  M=  16, -77,  20,  49, -76, -68, -15, -75,  22, -71,  -5, -53, -65,  60,  48, -34, -16, -70, -75,  -6;
/M: SY='F';  M= -43, -75,   9, -14,  70, -72, -55, -63,  38, -43,  -9, -10, -73,  35,  12,  -7, -34, -64, -55,  50;
/M: SY='H';  M= -64, -75, -64, -58,  -9, -73,  80, -13,  41,  30,   2, -57,   7, -53,  22,  -1,   0, -59, -74,   3;
/M: SY='E';  M= -60, -19, -44,  78,  -6,  22, -56, -80,  29, -55, -68,  22, -63, -43,  27, -36, -60, -75, -75, -27;
/M: SY='I';  M= -62, -71, -80, -77, -48, -83, -73,  67, -74,  45,  53,  -8, -77, -70, -75, -70, -16,  35, -76, -56;
/M: SY='E';  M= -39, -81,  44,  71, -75, -70, -11, -26, -22, -33, -67, -10,  65,  -8, -59, -22, -58, -71, -79,   1;
/M: SY='T';  M=  28, -68, -61, -58, -72, -41,  26, -11, -18, -50, -61, -53,  47,  -5, -63,  44,  64, -57, -82, -66;
/M: SY='C';  M= -63, 108, -72, -64, -77, -39, -74, -74, -68, -77, -69, -69, 101, -71, -77, -15, -59, -44,  31, -78;
/M: SY='I';  M= -31, -72, -76, -70, -29, -38,  10,  55, -18,  22,   3, -70, -10,  14, -69, -65,  -8,  51, -76, -25;
/M: SY='H';  M=  -6, -76,  -6,  53, -69, -70,  72, -68,  19,  18, -56, -55,  -4,  -2,  19,   5, -59, -67, -80, -59;
/M: SY='C';  M= -24, 102, -80, -77,  67, -38,   7,  19, -74, -30, -53, -69, -81, -78, -77, -64,   6,  20,  32, -47;
/M: SY='S';  M= -22, -64, -57, -57, -73, -51, -60, -69, -57, -74, -68, -45, -64, -50, -62, 103,  15, -24, -83, -66;
/M: SY='C';  M=  67,  75, -69, -65, -69, -28, -69, -16, -65, -18,  -3, -60, -70, -62, -69,  38,  -9, -22, -80, -69;
/M: SY='K';  M=   1, -73, -59, -51, -70, -41, -17, -65,  68,   7, -19,  12, -18,   9,  36,  -3,   2, -32, -76, -64;
/M: SY='W';  M= -37, -71, -33,  -2, -28,  -1, -31, -37, -30,  20, -56,  43, -69, -58,   8, -19,  58, -60,  86, -57;
/I:         I=-28; MD=-70;
/M: SY='P';  M= -30, -76, -64, -63, -65,  13,  28,  -6,  -5,  20,  31,  41,  44,  17, -64, -37,  -5, -42,  33, -63; D=-28;
/I:         I=-28; MD=-70;
/M: SY='H';  M= -15, -78,  32,   7,   4, -16,  33,   1,  20, -14, -63, -57,  -5, -57,  -2,  30, -59, -47,  12, -16; D=-28;
/I:         I=-28; MD=-70;
/M: SY='N';  M= -19, -80,  -7, -16, -88, -65, -59, -83, -60, -86,  -6,  82, -37,  42, -66,  29, -32, -82, -96, -78; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='V';  M= -12, -24, -39, -68, -17, -47, -17,  38, -19,  16, -20, -29, -20, -64, -49,  43, -51,  49, -78, -59;
/M: SY='N';  M= -29, -70, -50, -54, -74, -58,  19, -31,  31, -73, -27,  73,   8,  13, -30,  52,  17, -37, -84, -66;
/M: SY='E';  M= -31, -78,  45,  83, -83, -49, -11, -81, -46, -77, -71,  20,  -6,  39, -54,   1, -18, -76, -84, -70;
/M: SY='L';  M=  12, -69, -82, -75, -20, -79, -74,  47, -74,  54,  22, -76, -78, -70, -75, -36, -57,  41, -75, -56;
/M: SY='F';  M= -74, -73, -85, -81, 111, -82, -62, -49, -76,  -7, -49, -77, -85, -82, -73, -73, -67, -55,  27,  60;
/M: SY='Y';  M= -47, -75, -67, -20,   0, -36,  16,  14, -38, -53, -51, -64, -74, -60,  -4,  -5,  27,  21, -50,  97;
/M: SY='Y';  M=   1, -76, -64, -12,   8, -72,  11, -59,  50,  23,  -2, -61, -72,  46,  -1, -60, -61, -60, -58,  64;
/M: SY='C';  M=  40,  80, -78, -73, -54, -71, -72,  38, -72,  46,  16, -71, -77, -69, -74, -22, -58, -42, -76, -27;
/M: SY='Q';  M=  43,   1, -62, -49, -74, -64, -58, -38, -51, -21,  13, -56, -67,  93, -21, -22,  33, -16, -76, -63;
/M: SY='T';  M= -32, -73,  -1,  34, -74, -70, -59, -71,  61, -70,   7, -50, -62, -19,  30, -23,  62, -65,   6, -65;
/M: SY='M';  M=  74,   1, -69, -63, -67, -57, -66, -24, -63, -54,  75, -61, -67, -60, -67,   6,  22,  -7, -78, -65;
/M: SY='A';  M=  70, -64, -75, -68, -63, -63, -76,  22, -68, -50, -50, -69, -71, -67, -72, -32, -52,  64, -80, -66;
/M: SY='M';  M=  -7, -68, -69,  -9, -10, -75, -66,  13, -35,  37,  60, -64, -71,  17, -66, -30,  49,  13, -76, -57;
/M: SY='H';  M= -68, -77,  22,   8,  45, -70,  99, -69, -58, -62, -57,  37, -73, -19, -59, -59, -17, -71, -61,  70;
/I:         E1=0; IE=-380; DE=-380;
» more

Post-processing [info]

COMPETES_HIT_WITH PS51417; PS51418; PS51419; PS51420; PS51421; PS51422; PS51424

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 72 in 36 different sequences
Number of true positive hits 72 in 36 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Miro
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
36 sequences

GEM1_ASPFU  (Q4WN24), GEM1_ASPOR  (Q2UM43), GEM1_CANAL  (Q5ABR2), 
GEM1_CANGA  (Q6FIR8), GEM1_CRYNB  (P0CO79), GEM1_CRYNJ  (P0CO78), 
GEM1_EMENI  (Q5B5L3), GEM1_EREGS  (Q758X6), GEM1_GIBZE  (Q4I2W2), 
GEM1_KLULA  (Q6CY37), GEM1_NEUCR  (Q7RZA2), GEM1_SCHPO  (O59781), 
GEM1_USTMA  (Q4PB75), GEM1_YARLI  (Q6C2J1), GEM1_YEAST  (P39722), 
GEMA_DICDI  (Q55G45), MIRO1_ARATH (Q8RXF8), MIRO1_BOVIN (Q2HJF8), 
MIRO1_CAEBR (Q623S8), MIRO1_CAEEL (Q94263), MIRO1_CHICK (Q5ZM73), 
MIRO1_DANRE (Q6NVC5), MIRO1_HUMAN (Q8IXI2), MIRO1_MOUSE (Q8BG51), 
MIRO2_ARATH (F4J0W4), MIRO2_BOVIN (Q5E9M9), MIRO2_CHICK (Q5ZM83), 
MIRO2_DANRE (Q32LU1), MIRO2_HUMAN (Q8IXI1), MIRO2_MOUSE (Q8JZN7), 
MIRO2_PIG   (Q864R5), MIRO2_RAT   (Q7TSA0), MIRO2_XENTR (Q6DIS1), 
MIRO3_ARATH (Q9MA88), MIRO_DROME  (Q8IMX7), MIRO_DROPS  (Q298L5)
» more

PDB
[Detailed view]
11 PDB

4C0J; 4C0K; 4C0L; 5KSO; 5KSP; 5KSY; 5KSZ; 5KTY; 5KU1; 5KUT; 6D71