PROSITE entry PS51420
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PURL: https://purl.expasy.org/prosite/signature/PS51420
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General information about the entry
| Entry name [info] | RHO |
| Accession [info] | PS51420 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2008 CREATED;
18-JUN-2025 DATA UPDATE; 18-JUN-2025 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51417 |
| Associated ProRule [info] | PRU00754 |
Name and characterization of the entry
| Description [info] | Small GTPase Rho domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=180; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=175; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-4.0253091; R2=0.0040597; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-11689.4511719; R2=21.1734104; PRIORITY=1; TEXT='Heuristic 0.5%'; /CUT_OFF: LEVEL=0; SCORE=3086; H_SCORE=53652; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=2593; H_SCORE=43213; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-16; D=-40; I=-40; I0=-16; B1=*; E1=*; MI=-210; MD=-210; IM=-210; DM=-210; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-210; BD=-210; /M: SY='E'; M= -5, -61, 1, 20, -58, -15, 11, -18, 5, -46, -24, 16, 6, 19, 9, 14, 3, -27, -57, -40; /M: SY='Q'; M= 2, -66, -8, 20, -65, -15, 6, -54, 22, -52, -28, 17, 0, 30, 17, 17, 5, -43, -61, -43; /M: SY='P'; M= -11, -59, -11, 16, -13, -9, -10, -43, 22, -33, -22, 20, 33, 16, -10, 11, 2, -35, -56, -39; /M: SY='Q'; M= -6, -66, -9, 18, -64, -10, 4, -38, 22, -51, -28, 36, 15, 38, 0, 5, 2, -20, -61, -42; /M: SY='N'; M= 0, -64, 8, 20, -62, -26, -10, -32, 30, -29, -27, 33, 9, 11, 3, 2, -2, 7, -60, -42; /M: SY='K'; M= -9, -54, -18, 15, -11, -34, 8, -5, 41, -23, -17, -8, -44, 16, 15, 14, -1, -4, -52, 20; /M: SY='R'; M= -8, -62, -6, 27, -38, -17, 6, -20, 10, -25, -25, 7, -24, 17, 27, 25, 20, -38, -58, 14; /M: SY='I'; M= -19, 36, -65, -46, -20, -65, -31, 56, -31, 15, 22, -41, -57, -29, 6, -26, -11, 37, -32, -22; /M: /M: SY='C'; M= -17, 68, -84, -66, -15, -79, -48, 64, -62, 19, 20, -58, -69, -48, -61, -42, -21, 37, -44, -34; /M: SY='V'; M= -30, 0, -81, -64, 1, -81, -52, 20, -60, 3, 11, -58, -71, -48, -62, -43, -11, 83, -50, -39; /M: SY='V'; M= -29, 16, -83, -66, -30, -81, -52, 46, -62, 24, 0, -59, -71, -49, -63, -44, 14, 66, -49, -39; /M: SY='V'; M= -35, 13, -91, -75, -34, -90, -63, 36, -72, 23, -2, -69, -79, -59, -73, -54, -29, 79, -59, -48; /M: /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: /M: SY='G'; M= -8, -56, 6, 0, -55, 54, -14, -42, -2, -44, -7, 16, -44, 5, -16, 20, -10, -6, -56, -14; /M: SY='A'; M= 49, -56, -16, 8, -52, 18, -14, -39, 10, -23, -1, -8, -44, 29, -13, -4, -1, -31, -54, -39; /M: SY='C'; M= -18, 79, -78, -61, -32, -73, -48, 35, -57, -13, -2, -54, -66, -45, -59, -36, 10, 66, -49, -38; /M: /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: /I: I=-7; MI=0; MD=-36; IM=0; DM=-36; /M: SY='T'; M= -7, -37, -38, -34, -67, -36, -42, -50, -35, -58, -39, -26, -43, -27, -41, 24, 98, -35, -72, -60; /M: SY='C'; M= 15, 72, -38, -23, -47, -43, -28, -33, -22, -38, -19, -22, -44, -14, 2, 61, 27, -24, -54, -41; /M: SY='L'; M= -51, -57, -99, -82, -17,-103, -69, 9, -76, 75, 66, -79, -86, -59, -75, -67, -44, 12, -54, -49; /M: SY='L'; M= -52, -56,-104, -86, -17,-106, -72, 32, -82, 74, 57, -83, -88, -62, -79, -69, -44, 8, -55, -51; /M: SY='M'; M= -16, 19, -50, -32, -22, -60, 1, 31, -29, 5, 69, 23, -51, 17, -34, -20, -9, 24, -32, -4; /I: I=-12; MI=0; MD=-64; IM=0; DM=-64; /M: SY='S'; M= 18, 6, -37, -20, -35, -52, -23, -19, -19, -19, -7, -22, -47, -10, -5, 42, 33, 37, -43, -31; /M: SY='Y'; M= -30, -44, -58, -42, 61, -70, -17, -20, -21, -8, -8, -37, -61, -26, -2, -31, -23, -17, -9, 94; /I: I=-12; MI=0; MD=-64; IM=0; DM=-64; /M: SY='T'; M= 33, -18, -29, -12, -41, -50, -20, -27, -3, -32, -12, -16, -46, -4, -23, 27, 62, -12, -47, 1; /M: SY='Q'; M= -9, 29, -6, 3, -57, -50, -12, -28, 33, -34, -23, 3, -43, 46, 12, 29, 31, -35, -57, -40; /I: I=-6; MI=0; MD=-33; IM=0; DM=-33; /M: SY='N'; M= -29, -84, 40, 23, -84, 47, -17, -75, -2, -71, -50, 67, -45, 3, -27, -15, -23, -62, -80, -58; D=-6; /I: I=-6; MI=0; MD=-33; IM=0; DM=-33; /M: SY='S'; M= 12, 16, -5, 27, -33, -10, -12, -43, 18, -43, -22, -6, -6, 18, -13, 28, 20, -34, -56, 6; /M: SY='F'; M= -29, -39, -70, -53, 86, -73, -25, 11, -49, 5, 2, -45, -64, -35, -50, -34, 6, -7, -16, 49; /I: I=-9; MI=0; MD=-45; IM=0; DM=-45; /M: SY='P'; M= -1, -2, -1, -1, -3, -2, -1, -2, -1, -1, -1, 0, 4, 0, -1, 0, 1, -2, -3, -2; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='E'; M= -9, -67, -10, 51, -65, -25, -11, -54, 13, -39, -29, 8, -42, 30, 0, 16, 44, -31, -62, -44; /M: SY='E'; M= 2, -69, 30, 36, -68, -26, 13, -34, 9, -29, -31, 8, -41, 35, 16, 11, 5, -12, -63, -44; /M: SY='Y'; M= -54, -61, -78, -68, 37, -88, -13, -32, -63, -25, -22, -52, -78, -46, -63, -51, -47, -8, 6, 120; /I: I=-3; MI=0; MD=-14; IM=0; DM=-14; /M: SY='V'; M= -6, -45, -26, 12, -38, -54, 3, 12, 6, -28, -9, -14, -46, 34, -2, -7, -2, 49, -44, 2; /M: SY='P'; M= -9, -42, -25, -24, -75, -8, -39, -65, -32, -68, -47, -21, 105, -23, -40, 11, -13, -46, -77, -65; /M: SY='T'; M= -6, -37, -38, -32, -67, -35, -40, -51, -34, -59, -39, -25, -43, -26, -41, 40, 94, -36, -72, -60; /I: I=-12; MI=0; MD=-64; IM=0; DM=-64; /M: SY='V'; M= 6, -32, -56, -38, 0, -63, 9, 22, -35, -12, 3, -36, -55, -24, -39, -24, 8, 68, -35, -24; /M: SY='F'; M= -29, -39, -18, -50, 87, -71, -19, -14, -46, 1, -3, -42, -62, -32, -47, -32, -21, 2, 68, 32; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='E'; M= -22, -75, 59, 66, -74, -47, -13, -18, -1, -61, -38, -1, -43, 8, -17, 5, 6, -51, -70, -50; /I: I=-5; MI=0; MD=-27; IM=0; DM=-27; /M: SY='N'; M= -8, -75, 17, 30, -74, -48, 4, -64, 11, -61, -38, 85, -43, 9, 1, -10, 2, -52, -70, -50; /M: SY='Y'; M= -24, -42, -47, -30, 43, -64, 18, -19, -27, -23, -7, -30, -56, -17, -1, -24, 16, -16, -18, 93; /M: SY='S'; M= -4, -41, -31, -14, -33, -27, -19, 10, -14, -11, 7, 6, -48, -5, -24, 42, 39, 17, -41, -9; /M: SY='H'; M= 28, 3, -30, -12, -17, -55, 43, -20, -12, -13, -6, 5, -47, -4, 3, -14, 37, 24, -42, -28; /M: SY='D'; M= -8, -2, 43, 17, -63, -49, -11, -52, 4, -20, -28, 32, -9, 28, -10, 25, 14, -16, -61, -43; /M: SY='V'; M= -5, -1, -67, -33, 7, -64, -30, 39, -44, 21, 23, -41, -55, -30, -27, -25, -4, 49, -30, -1; /I: I=-10; MI=0; MD=-50; IM=0; DM=-50; /M: SY='E'; M= 0, -1, 0, 0, 0, -1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, -1, 0; D=-10; /I: I=-10; MI=0; MD=-50; IM=0; DM=-50; /M: SY='V'; M= 0, 0, -1, 0, 0, -1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0; /I: I=-5; MI=0; MD=-28; IM=0; DM=-28; /M: SY='D'; M= -1, -4, 3, 1, -4, 0, -1, -3, 1, -3, -2, 3, -2, 1, 0, 0, -1, -3, -4, -3; /M: SY='N'; M= -1, -4, 2, 1, -4, 2, -1, -3, 1, -3, -2, 2, -2, 1, 0, 0, 0, -3, -3, -2; /I: I=-12; MI=0; MD=-64; IM=0; DM=-64; /M: SY='Q'; M= -6, -67, 6, 17, -66, -48, -10, -14, 52, -53, -30, 10, -41, 53, 15, -6, -4, -15, -62, -43; /I: I=-10; MI=0; MD=-54; IM=0; DM=-54; /M: SY='P'; M= -9, -63, 4, 19, -60, -50, 10, -12, 15, -30, -25, -4, 38, 30, 18, 13, 6, 3, -59, -41; /M: SY='V'; M= -9, 11, -69, -50, -3, -64, -8, 49, -45, 4, 21, -42, -56, -31, -44, -26, -10, 51, -29, 26; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='E'; M= -18, -69, -10, 49, -69, -49, 31, -35, 27, -43, -31, 34, -42, 12, 16, 27, 11, -46, -64, -45; /M: SY='L'; M= -50, -55,-102, -85, -21,-105, -73, 39, -80, 74, 14, -82, -88, -64, -80, -69, -43, 22, -58, -52; /M: SY='S'; M= 7, -68, 2, 16, -67, 13, 15, -56, 5, -54, -30, 24, -42, 25, 22, 39, 6, -33, -63, -44; /I: I=-11; MI=0; MD=-56; IM=0; DM=-56; /M: SY='L'; M= -43, -8, -93, -75, 5, -93, -59, 24, -71, 74, 30, -70, -79, -54, -70, -56, -35, 2, -48, -40; /M: SY='W'; M= -31, -4, -68, -52, 16, -73, -19, -15, -47, -16, -4, -43, -64, -33, -48, -34, -24, 4, 145, 36; /I: I=-7; MI=0; MD=-36; IM=0; DM=-36; /M: SY='D'; M= -39, -96, 104, 25, -95, -45, -25, -88, -24, -86, -68, 2, -49, -6, -45, -23, -36, -75, -92, -69; D=-7; /I: I=-7; MI=0; MD=-36; IM=0; DM=-36; /M: SY='T'; M= -12, -42, -31, -19, -51, -45, -27, -6, -19, -41, -22, 6, -46, -12, -27, 6, 90, -24, -57, -43; /M: SY='A'; M= 63, -47, 1, -8, -5, -9, -21, -38, -12, -42, -21, -13, -44, -3, -24, 27, -9, -29, -56, -41; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='G'; M= -1, -54, 17, -7, -79, 82, -33, -68, -28, -70, -50, -12, -45, -15, -41, -10, -18, -51, -80, -64; /M: SY='Q'; M= -18, -65, 11, 5, -19, -22, -12, -51, 3, -30, -28, 13, -43, 89, -12, 20, -11, -41, -61, -43; /I: I=-9; MI=0; MD=-45; IM=0; DM=-45; /M: SY='E'; M= -9, -80, 42, 72, -80, -44, -15, -71, -5, -67, -45, 20, 5, 6, -22, -1, -19, -58, -75, -54; D=-9; /I: I=-9; MI=0; MD=-45; IM=0; DM=-45; /M: SY='E'; M= 0, -1, 1, 1, -1, -1, 0, -1, 0, -1, 0, 0, 0, 0, 0, 0, 0, -1, -1, 0; D=-9; /I: I=-9; MI=0; MD=-45; IM=0; DM=-45; /M: SY='Y'; M= -59, -63, -84, -75, 69, -92, 34, -42, -70, -7, -29, -54, -81, -48, -67, -55, -51, -42, 12, 108; /M: SY='D'; M= -20, -75, 71, 19, -75, -48, 35, -65, 14, -61, -37, 13, -21, 11, 19, 18, -13, -52, -69, -49; /I: I=-12; MI=0; MD=-61; IM=0; DM=-61; /M: SY='R'; M= -25, -75, -14, 20, -76, -53, -11, -64, 34, -60, -37, 40, -46, 24, 69, 7, -17, -53, -66, -50; D=-12; /I: I=-12; DM=-61; /M: SY='L'; M= -18, -35, -7, -30, -16, -62, -27, 21, -29, 51, 2, -31, -53, -18, -35, -4, 5, 21, -37, -25; D=-12; /I: I=-12; DM=-61; /M: SY='R'; M= -36, -74, -35, -15, -80, -61, -15, -65, 30, -61, -41, -19, -9, 5, 96, -26, -27, -57, -65, -55; /M: SY='P'; M= -20, -60, -15, -3, -64, -49, -17, -52, 1, -52, -31, -10, 88, 24, 20, 20, -15, -42, -63, -47; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='L'; M= -34, -43, -78, -61, 19, -81, -45, 28, -57, 68, 12, -56, -70, -42, -57, -16, -26, 2, -39, -27; /M: SY='S'; M= 7, 41, -26, 7, -15, -36, -17, -14, 5, -30, -10, -14, -46, -1, -20, 61, 6, -19, -46, -32; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='Y'; M= -68, -70, -85, -80, 42, -95, -9, -46, -74, -35, -34, -57, -85, -53, -71, -61, -61, -48, 12, 125; /M: SY='P'; M= -3, -63, -10, 4, -65, -8, -13, -53, 1, -52, -30, 22, 64, 42, -5, 21, 7, -42, -63, -45; /I: I=-2; MI=0; MD=-13; IM=0; DM=-13; /M: SY='D'; M= -20, -76, 58, 24, -76, -19, 19, -66, 10, -62, -38, 39, -42, 46, 9, -1, -13, -53, -70, -49; D=-2; /I: I=-2; MI=0; MD=-13; IM=0; DM=-13; /M: SY='T'; M= 27, -38, -36, -21, -45, -45, -26, -5, -20, -34, -16, -21, -45, -12, -30, 35, 65, 2, -52, -39; D=-2; /I: I=-2; DM=-13; /M: SY='D'; M= -31, -88, 89, 13, -85, -46, 39, -78, -10, -74, -52, 44, -46, 9, -28, -8, -25, -65, -82, -59; /M: SY='V'; M= 4, 5, -82, -65, -33, -82, -53, 47, -62, 11, -2, -59, -72, -50, -64, -44, -13, 71, -52, -41; /M: SY='F'; M= -38, -43, -93, -76, 63, -90, -56, 39, -71, 28, 10, -68, -77, -55, -70, -53, -30, 54, -46, -36; /I: I=-8; MI=0; MD=-41; IM=0; DM=-41; /M: SY='L'; M= -49, -54,-102, -84, -8,-102, -68, 28, -80, 71, 59, -80, -85, -60, -78, -66, -41, 20, -53, -49; /M: SY='I'; M= -18, -45, -93, -76, -25, -93, -62, 61, -72, 53, 32, -71, -80, -57, -72, -56, -32, 33, -54, -46; /M: SY='C'; M= -6, 124, -62, -50, -40, -30, -42, -13, -43, 2, -14, -39, -51, -35, -46, -14, -12, -7, -52, -40; /M: SY='F'; M= -70, -69, -93, -88, 105, -99, -9, -44, -83, -31, -30, -60, -87, -57, -76, -64, -62, -47, 13, 80; /M: SY='S'; M= 24, -58, 41, 0, -73, -42, -22, -61, -13, -62, -40, -7, -43, -3, -27, 74, -14, -47, -73, -55; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='V'; M= -23, -43, -94, -79, -39, -95, -70, 66, -76, 6, -5, -73, -84, -64, -78, -59, -17, 72, -66, -55; /M: SY='D'; M= 9, -57, 45, 8, -52, -36, -13, 5, 0, -41, 8, 5, -43, 7, -14, 34, 3, 4, -54, -38; /M: SY='N'; M= -18, -32, 8, 11, -68, -40, -11, -57, 9, -55, -31, 67, -42, 24, 19, 45, -11, -46, -64, -45; /M: SY='P'; M= -20, -67, -15, 10, -36, -52, 26, -54, 23, -52, -30, -6, 67, 23, 47, -10, -13, -44, -61, -45; /M: SY='T'; M= 12, -69, 25, 35, -68, -48, -11, -58, 3, -55, -32, 41, -20, 11, -12, 19, 41, -28, -65, -46; /I: I=-7; MI=0; MD=-38; IM=0; DM=-38; /M: SY='S'; M= -6, -38, -36, -32, -72, -34, -42, -58, -35, -65, -44, -25, -42, -27, -42, 93, 27, -41, -76, -64; /M: SY='F'; M= -36, -44, -81, -65, 72, -81, -29, -6, -60, 44, 17, -54, -70, -43, -58, -43, -29, -1, -16, 57; /M: SY='D'; M= -5, -71, 48, 45, -71, -48, 19, -39, 11, -24, -33, 29, -42, 31, -10, 3, 0, -48, -66, -46; /M: SY='N'; M= -14, -67, -1, 3, -68, -47, 36, -61, -5, -60, -39, 95, -46, 2, -18, 18, -18, -50, -68, -49; /M: SY='V'; M= 3, 26, -86, -69, -34, -83, -56, 54, -65, 0, -3, -62, -74, -53, -66, -46, -24, 70, -54, -43; /I: I=-13; MD=-67; /M: SY='K'; M= -1, -3, -1, 1, -2, -2, -1, -1, 2, 1, 0, 0, -2, 1, 0, 1, 0, -1, -3, -1; D=-13; /I: I=-13; MI=-67; IM=-67; DM=-67; /M: SY='E'; M= -18, -71, 30, 39, -70, -48, -10, -31, 36, -57, -33, 30, -42, 12, -10, 10, 38, -47, -65, -24; /M: SY='K'; M= -21, -62, -19, 5, -59, -53, -12, -46, 75, -24, 31, 3, -45, 8, 8, -1, -13, -38, -57, -16; /M: /M: SY='Y'; M= -3, -33, -45, -13, 21, -59, -7, 20, -13, 12, 14, 17, -50, 2, -8, -18, -9, 18, 5, 35; /M: SY='P'; M= -17, -58, 5, 1, -17, -6, -14, -44, -1, -45, -24, -7, 73, 23, -15, 9, 24, -35, -58, -41; /M: /M: SY='I'; M= -25, -43, -94, -78, -38, -95, -69, 79, -75, 11, -4, -73, -83, -63, -77, -59, -12, 56, -64, -54; /M: SY='R'; M= -14, -67, -15, 3, -66, -52, -11, -41, 43, -12, -30, 35, -44, 28, 49, -3, 17, -44, -61, -44; /M: SY='H'; M= -17, -38, 19, 28, -70, -49, 74, -59, 22, -41, -32, -2, -42, 50, 10, 11, 4, -47, -65, -45; /I: I=-2; MI=0; MD=-13; IM=0; DM=-13; /M: SY='Y'; M= -18, -10, -42, -25, 54, -58, 35, 4, -23, -18, -1, 31, -50, -13, -30, -19, 3, -8, -28, 55; D=-2; /I: I=-2; DM=-13; /M: SY='C'; M= 1, 94, -50, -32, -22, -59, -25, 8, -29, 11, 23, 4, -51, -19, -34, -4, 1, -2, -32, 7; D=-2; /I: I=-2; MI=0; MD=-13; IM=0; DM=-13; /M: SY='P'; M= -14, -65, -7, 15, -65, -37, -15, -53, 11, -52, -31, -6, 88, 13, 4, -3, -16, -43, -63, -47; D=-2; /I: I=-2; MI=0; MD=-13; IM=0; DM=-13; /M: SY='S'; M= -17, -1, 7, 13, -66, 14, 28, -56, 19, -53, -30, 28, -41, 29, 10, 30, 12, -44, -63, -44; D=-2; /I: I=-2; MI=0; MD=-13; IM=0; DM=-13; /M: SY='T'; M= 21, -34, -49, -31, -26, -61, -27, 37, -29, -8, 1, -31, -9, -19, -35, -21, 43, 37, -37, -11; /I: I=-12; MI=0; MD=-64; IM=0; DM=-64; /M: SY='P'; M= -23, -65, -14, 0, -63, -52, -14, -51, 31, -50, -29, 14, 86, 7, 10, -13, -15, -42, -60, -14; /M: SY='I'; M= -26, -34, -77, -60, -24, -76, -44, 63, -55, 18, 39, -53, -66, -42, -56, -24, -11, 51, -42, -12; /M: SY='I'; M= -43, -46,-101, -85, -31,-100, -72, 69, -81, 31, 32, -79, -86, -66, -81, -64, -36, 59, -62, -54; /M: SY='L'; M= -49, -56, -93, -79, -20, -96, -67, 10, -71, 79, 13, -75, -84, -58, -71, -62, -43, 21, -55, -46; /M: SY='V'; M= -27, 12, -75, -58, -29, -77, -47, 34, -54, 1, 1, -53, -68, -13, -56, -39, -21, 79, -47, -36; /M: SY='G'; M= 13, -50, -1, -10, -71, 77, -29, -58, -20, -61, -40, -14, -44, -11, -12, -8, -14, -44, -72, -58; /M: SY='T'; M= -17, 67, -55, -37, -27, -59, -31, 10, -34, 17, 0, -34, -53, -24, -39, -11, 68, 1, -39, -28; /M: SY='K'; M= -36, -80, -23, -9, -84, -60, -14, -70, 84, -64, -44, -14, -53, 65, 13, -25, -27, -61, -68, -56; /M: SY='T'; M= -4, 39, -46, -28, -24, -59, -24, 24, -15, 13, 19, -11, -51, -16, -32, 25, 42, 3, -34, -22; /M: /M: SY='L'; M= -41, -53, -70, -55, -19, -84, -47, -1, -44, 77, 28, -54, -73, 2, -46, -47, -34, -10, -47, -37; /I: I=-12; MI=0; MD=-61; IM=0; DM=-61; /M: SY='R'; M= 0, -1, 0, 0, -1, -1, 0, -1, 0, 0, 0, 0, -1, 0, 1, 0, 0, -1, -1, 0; /M: SY='E'; M= 0, -1, 0, 0, -1, 0, 0, 0, 0, -1, 0, 0, 0, 0, 0, 0, 0, -1, -1, 0; /M: SY='D'; M= 0, 0, 1, 0, -1, -1, 0, -1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, -1, 0; /I: I=-5; MD=-25; /M: SY='D'; M= 0, -1, 0, 0, -1, 0, 0, -1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, -1, 0; D=-5; /I: I=-5; MD=-25; /M: SY='N'; M= 2, -10, 0, 3, -10, -3, 3, -8, 3, -3, -4, 6, -1, 2, -2, 3, -1, -3, -10, -7; D=-5; /I: I=-5; MD=-25; /M: SY='T'; M= -6, -8, -11, 10, -7, -22, 6, 0, -4, -2, -3, -6, -10, 6, -8, -3, 16, 3, -17, 4; D=-5; /I: I=-5; MD=-25; /M: SY='L'; M= 0, -17, -6, -4, -14, -17, -7, 1, 5, 14, -2, -6, -19, 5, -3, -3, -3, 3, -16, -11; D=-5; /I: I=-5; MD=-25; /M: SY='N'; M= -2, -23, 8, 8, -21, -20, -4, -3, 3, -17, 5, 11, -9, 4, 4, 0, -3, 1, -22, -1; D=-5; /I: I=-5; MI=0; MD=-25; IM=0; DM=-25; /M: SY='E'; M= 3, -26, -4, 13, -25, -14, -4, -20, 12, -10, -11, 2, -10, 12, 7, -3, 0, -16, -24, -17; D=-5; /I: I=-5; DM=-25; /M: SY='L'; M= -8, -17, -14, -8, -12, -23, -8, 0, -4, 18, -1, 2, -20, -3, 4, -7, -5, -4, -16, -10; D=-5; /I: I=-5; DM=-25; /M: SY='Q'; M= -3, -5, 5, 2, -23, -19, -4, -18, 7, -14, -9, -1, -16, 12, 11, 11, 1, -14, -23, -16; D=-5; /I: I=-5; DM=-25; /M: SY='E'; M= -2, -24, -4, 11, -23, -19, 7, -7, 9, -13, -9, 3, 4, 10, 3, -2, -1, -14, -23, -8; D=-5; /I: I=-5; DM=-25; /M: SY='Q'; M= 0, -8, -11, 1, -33, -14, 7, -24, 13, -11, 1, 14, -29, 24, -7, -1, -5, -19, -35, -10; D=-5; /I: I=-5; MI=0; MD=-25; IM=0; DM=-25; /M: SY='K'; M= -11, -62, -10, 9, -61, -9, 3, -51, 42, -26, -28, 17, -18, 35, 33, 0, -1, -26, -57, -40; D=-5; /I: I=-5; DM=-25; /M: SY='Q'; M= 0, -1, 0, 0, 0, 0, 0, -1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, -1, 0; D=-5; /I: I=-5; DM=-25; /M: SY='E'; M= 0, -3, 1, 2, -3, -1, 1, -2, 1, -2, -2, 1, -1, 1, 0, 1, 1, -2, -3, -2; D=-5; /I: I=-5; DM=-25; /M: SY='P'; M= 0, 0, -1, -1, 1, -3, -1, 1, -1, 0, 1, -1, 3, -1, -1, -1, 0, 0, -2, 0; D=-5; /I: I=-5; DM=-25; /M: SY='V'; M= -32, -39, -43, -64, -32, -84, -55, 60, -62, 9, 18, -60, -73, -50, -64, -47, -25, 68, -53, -43; /M: SY='T'; M= -18, -65, 9, 12, -64, -47, -12, -53, 9, -52, -30, 22, 29, 17, -12, 41, 50, -43, -62, -44; /M: SY='Y'; M= 1, -51, -19, 8, -13, -51, 22, -20, 5, -35, -15, -9, 23, 34, -7, -10, 12, -25, -49, 64; /M: SY='E'; M= -11, -69, 23, 58, -68, -47, 13, -33, 20, -55, -7, -1, -11, 33, -9, 12, 8, -46, -63, -44; /M: SY='Q'; M= -2, -68, 9, 52, -68, -48, 5, -57, 18, -55, 27, -2, -41, 63, 4, 1, -10, -46, -63, -44; /M: SY='G'; M= 27, -36, -35, -30, -68, 75, -39, -35, -34, -60, -40, -23, -41, -25, -41, 8, -8, -37, -72, -61; /M: SY='Q'; M= -6, 1, 0, 13, -31, -37, 0, 9, 14, 7, 4, -8, -32, 22, 7, -7, 1, 2, -34, -24; /M: SY='E'; M= 21, -66, 6, 42, -65, -18, -10, -55, 17, -27, -4, 24, -41, 24, 10, 11, -9, -28, -61, -43; /M: SY='M'; M= -3, -1, -62, -44, -20, -65, -32, 14, -12, 37, 71, -40, -56, -29, -43, -27, -12, 34, -33, -23; /M: SY='A'; M= 60, 18, -27, -10, -44, -49, -19, -30, -1, -34, -15, -15, -44, 8, 11, 17, -9, -16, -49, -35; /I: I=-9; MI=0; MD=-47; IM=0; DM=-47; /M: SY='K'; M= -3, -12, 0, 4, -12, -6, -2, -10, 11, -10, -6, 2, -7, 6, 4, -2, -2, -8, -11, -8; /M: SY='Q'; M= 0, -12, 1, 9, -12, -8, -2, -10, 6, -10, -6, 0, -7, 9, 4, 1, -2, -8, -11, -8; /M: SY='I'; M= -2, -1, -5, -4, -1, -5, -3, 4, -4, 1, 2, -4, -4, -3, -4, -3, -2, 2, -3, -2; /M: SY='G'; M= -1, -3, 1, 0, -3, 2, 0, -3, 1, -3, -2, 2, -2, 0, 1, 0, -1, -2, -3, -2; /I: I=-5; MD=-26; /M: SY='A'; M= 4, 0, -2, -2, -1, -1, -2, -1, -2, -2, -1, -1, -2, -1, -2, 0, 0, -1, -3, -2; D=-5; /I: I=-5; MI=0; MD=-26; IM=0; DM=-26; /M: SY='V'; M= 5, 7, -43, -7, 17, -57, -22, 21, 13, -4, 13, -26, -49, -2, -30, 6, 10, 29, -33, -10; D=-5; /I: I=-5; DM=-26; /M: SY='K'; M= 16, 11, -3, 1, -51, 2, 7, -16, 24, -26, 11, 2, -3, 14, 10, 11, 1, -18, -52, -37; /M: SY='Y'; M= -59, -63, -79, -70, 49, -89, 29, -43, -65, -13, -29, -51, -79, -45, -63, -53, -51, -43, 11, 114; /M: SY='L'; M= -18, 0, -68, -49, -7, -64, -31, 32, -45, 42, 39, -42, -55, -31, -44, -18, 5, 22, -29, 29; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='E'; M= -26, -72, 2, 87, -28, -48, -16, -58, -4, -56, -38, -3, -46, 23, -17, -15, -20, -49, -66, -47; /M: SY='C'; M= 4, 121, -61, -51, -52, -13, -45, -31, -48, -43, -25, -34, -43, -37, -50, -4, 24, -10, -61, -52; /M: /M: SY='A'; M= 65, -36, -43, -31, -59, -37, -37, -41, -31, -49, -29, -25, -43, -22, -39, 48, 13, 7, -65, -53; /M: SY='K'; M= 2, -42, -30, -13, 9, -55, -18, -19, 37, 32, -6, -18, -47, -4, 18, -15, -10, 4, -41, -29; /I: I=-11; MI=0; MD=-56; IM=0; DM=-56; /M: SY='T'; M= -5, 2, -1, 0, -16, -53, 2, -28, 12, -1, 16, -12, -45, 13, -18, 16, 57, -22, -47, -32; /M: SY='Q'; M= -18, -68, -11, 6, -67, -16, 13, -56, 28, -53, 9, 46, -42, 58, 17, 18, -10, -44, -63, -1; /M: SY='E'; M= -12, -69, 8, 44, -1, -49, -10, -35, 42, -40, -31, 5, -42, 44, 23, -6, -10, -45, -63, -45; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='N'; M= -9, -1, -25, -15, -68, 59, -29, -56, -19, -58, -36, 61, -42, -10, -30, 24, -9, -41, -69, -55; /I: I=-10; MI=0; MD=-54; IM=0; DM=-54; /M: SY='V'; M= -43, -47,-100, -84, -32,-101, -73, 46, -81, 43, 3, -79, -87, -67, -81, -65, -37, 71, -64, -55; /M: SY='K'; M= -18, -73, 19, 32, -74, -49, 35, -64, 44, -60, -35, 39, -42, 32, 21, 7, -5, -51, -67, -47; /M: SY='E'; M= 1, -75, 49, 61, -75, -48, -12, -65, 1, -42, -38, 0, -43, 37, -14, 9, 4, -52, -70, -50; /M: SY='V'; M= -15, -43, -92, -76, -38, -94, -69, 46, -74, 13, -4, -72, -83, -62, -76, -58, -32, 81, -65, -54; /M: /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='D'; M= -12, -73, 50, 45, -73, -48, 23, -64, 20, -46, -35, 19, -42, 28, 15, 0, 6, -51, -67, -47; /M: SY='E'; M= 1, 1, -15, 44, -27, -51, -12, -42, 20, -36, -22, 16, -43, 27, -4, 4, 27, 7, -56, -39; /M: SY='A'; M= 68, -39, -38, -22, -42, -33, -27, -22, -21, -15, 7, -23, -47, -13, -30, 14, -9, 6, -50, -37; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='I'; M= 1, -2, -3, -2, -1, -2, -2, 3, -2, 0, 0, -2, -3, -1, -2, 0, 1, 2, -2, -1; /M: SY='R'; M= -17, -64, 13, 18, -62, -50, 20, -12, 28, -16, 9, 23, -42, 11, 48, -7, -10, -15, -60, -42; /M: SY='V'; M= 26, 31, -51, -33, -22, -60, 2, 19, -31, -4, 5, -31, -52, -19, -35, -4, 31, 40, -32, -8; /I: I=-13; MI=0; MD=-67; IM=0; DM=-67; /M: SY='A'; M= 38, 34, -43, -26, -8, -10, 11, 5, -24, -10, 2, -26, -50, -14, -31, 1, 8, 15, -34, 19; /I: I=-13; E1=0; MI=0; IE=0; DE=-67;» more |
Post-processing [info]
| COMPETES_HIT_WITH | PS51417; PS51418; PS51419; PS51421; PS51422; PS51423; PS51424; PS52057 |
Numerical results [info]
| Total number of hits | 162 in 162 different sequences |
| Number of true positive hits | 162 in 162 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 99.39 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | N_Hulo, L_Cerutti |
| Version [info] | 7 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
162 sequences
CDC42_AEDAE (Q16YG0), CDC42_ANOGA (Q17031), CDC42_BOVIN (Q2KJ93), CDC42_CAEEL (Q05062), CDC42_CANAL (P0CY33), CDC42_CANAW (C4YDI6), CDC42_CANLF (P60952), CDC42_CHICK (Q90694), CDC42_COLGL (O94103), CDC42_DROME (P40793), CDC42_DROPS (Q29HY3), CDC42_EREGS (Q9HF56), CDC42_HUMAN (P60953), CDC42_MACFA (Q4R4R6), CDC42_MOUSE (P60766), CDC42_PIG (Q007T2), CDC42_RAT (Q8CFN2), CDC42_SCHPO (Q01112), CDC42_YEAST (P19073), CRL1_CANAW (P33153), RAC10_ARATH (O82481), RAC11_ARATH (P92978), RAC13_GOSHI (Q41253), RAC1A_DICDI (P34144), RAC1B_DICDI (P34145), RAC1C_DICDI (P34146), RAC1_ARATH (Q38902), RAC1_BETVU (Q39435), RAC1_BOVIN (P62998), RAC1_CAEEL (Q03206), RAC1_CANLF (P62999), RAC1_DROME (P40792), RAC1_HUMAN (P63000), RAC1_LOTJA (O04369), RAC1_MOUSE (P63001), RAC1_ORYSJ (Q9SSX0), RAC1_RAT(Q6RUV5), RAC1_STIJA (A0A286QZ36), RAC2_ARATH (Q38903), RAC2_BOVIN (Q9TU25), RAC2_CAEEL (Q94124), RAC2_CAVPO (O88931), RAC2_DROME (P48554), RAC2_HUMAN (P15153), RAC2_LOTJA (Q40220), RAC2_MOUSE (Q05144), RAC2_ORYSJ (Q68Y52), RAC3_ARATH (Q38912), RAC3_HUMAN (P60763), RAC3_MOUSE (P60764), RAC3_ORYSJ (Q6Z808), RAC4_ARATH (Q38919), RAC4_ORYSJ (Q67VP4), RAC5_ARATH (Q38937), RAC5_ORYSJ (Q6EP31), RAC6_ARATH (Q9SBJ6), RAC6_ORYSJ (Q6ZHA3), RAC7_ARATH (O82480), RAC7_ORYSJ (Q6Z7L8), RAC8_ARATH (Q9SU67), RAC9_ARATH (Q9XGU0), RAC9_GOSHI (Q41254), RACA_DICDI (P34147), RACA_ENTH1 (Q24814), RACB_DICDI (P34148), RACB_ENTH1 (Q24815), RACC_DICDI (P34149), RACC_ENTH1 (Q24816), RACD_DICDI (P34150), RACD_ENTH1 (Q24817), RACE_DICDI (Q23862), RACF1_DICDI (O96390), RACF2_DICDI (Q9GPS3), RACG_DICDI (Q9GPS0), RACG_ENTH1 (O76321), RACH_DICDI (Q9GPR7), RACI_DICDI (Q9GPR2), RACJ_DICDI (Q9GPQ9), RACL_DICDI (Q9GPQ8), RACM_DICDI (Q54HZ7), RACN_DICDI (Q54YY4), RACO_DICDI (Q54Z85), RHBT1_HUMAN (O94844), RHBT1_MOUSE (Q9DAK3), RHBT2_HUMAN (Q9BYZ6), RHBT2_MOUSE (Q91V93), RHO1_CAEEL (Q22038), RHO1_CANAL (O42825), RHO1_DROME (P48148), RHO1_ENTH1 (P31021), RHO1_EREGS (Q9HF54), RHO1_KLULA (Q8J212), RHO1_PEA(Q35638), RHO1_SCHPO (Q09914), RHO1_YEAST (P06780), RHO2_SCHPO (Q10133), RHO2_YEAST (P06781), RHO3_EREGS (Q9HF51), RHO3_SCHCO (Q9P8J9), RHO3_SCHPO (O13928), RHO3_YEAST (Q00245), RHO4_EREGS (Q9P8V0), RHO4_SCHPO (Q874R1), RHO4_YEAST (Q00246), RHO5_SCHPO (Q9HE04), RHO5_YEAST (P53879), RHOAA_DANRE (Q6NUX8), RHOAB_DANRE (Q6DHM9), RHOAC_DANRE (Q7T2E8), RHOAD_DANRE (Q6DHE8), RHOA_BOVIN (P61585), RHOA_CANLF (P24406), RHOA_EMENI (Q9C3Y4), RHOA_HUMAN (P61586), RHOA_MOUSE (Q9QUI0), RHOA_PONAB (Q5REY6), RHOA_RAT(P61589), RHOB_BOVIN (Q3ZBW5), RHOB_HUMAN (P62745), RHOB_MOUSE (P62746), RHOB_RAT(P62747), RHOC_BOVIN (Q1RMJ6), RHOC_CHICK (Q9PSX7), RHOC_EMENI (Q96WY0), RHOC_HUMAN (P08134), RHOC_MOUSE (Q62159), RHOC_PONAB (Q5RCK9), RHOD_MOUSE (P97348), RHOF_BOVIN (Q3SZA1), RHOF_HUMAN (Q9HBH0), RHOF_MOUSE (Q8BYP3), RHOG_CRICR (P84097), RHOG_HUMAN (P84095), RHOG_MOUSE (P84096), RHOH_BOVIN (Q2HJG3), RHOH_HUMAN (Q15669), RHOH_MOUSE (Q9D3G9), RHOJ_HUMAN (Q9H4E5), RHOJ_MOUSE (Q9ER71), RHOL_DROME (Q24192), RHOQ_HUMAN (P17081), RHOQ_MOUSE (Q8R527), RHOQ_RAT(Q9JJL4), RHOU_BOVIN (A5D7J5), RHOU_HUMAN (Q7L0Q8), RHOU_MOUSE (Q9EQT3), RHOV_BOVIN (Q17QI8), RHOV_HUMAN (Q96L33), RHOV_MOUSE (Q8VDU1), RHOV_RAT(Q9Z1Y0), RHO_APLCA (P01122), RHO_DIPOM (P22122), RND1_BOVIN (Q2HJ68), RND1_HUMAN (Q92730), RND1_MOUSE (Q8BLR7), RND2_HUMAN (P52198), RND2_MOUSE (Q9QYM5), RND3_HUMAN (P61587), RND3_MOUSE (P61588), RND3_PIG(O77683), RND3_PONAB (Q5R9F4), RND3_RAT(Q6SA80)» more
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| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
RHOD_HUMAN (O00212) |
| PDB [Detailed view] |
278 PDB
1A2B; 1A4R; 1AJE; 1AM4; 1AN0; 1CC0; 1CEE; 1CF4; 1CXZ; 1DOA; 1DPF; 1DS6; 1E0A; 1E96; 1EES; 1FOE; 1FTN; 1G4U; 1GRN; 1GWN; 1GZS; 1HE1; 1HH4; 1I4D; 1I4L; 1I4T; 1KI1; 1KMQ; 1KZ7; 1KZG; 1LB1; 1M7B; 1MH1; 1NF3; 1OW3; 1RYF; 1RYH; 1S1C; 1TX4; 1X86; 1XCG; 1Z2C; 2ASE; 2ATX; 2C2H; 2CLS; 2DFK; 2FJU; 2FV8; 2G0N; 2GCN; 2GCO; 2GCP; 2H7V; 2IC5; 2J0V; 2J1L; 2KB0; 2NGR; 2NTY; 2NZ8; 2ODB; 2OV2; 2P2L; 2Q3H; 2QME; 2QRZ; 2REX; 2RGN; 2RMK; 2V55; 2VRW; 2W2T; 2W2V; 2W2X; 2WBL; 2WKP; 2WKQ; 2WKR; 2WM9; 2WMN; 2WMO; 2YIN; 3A58; 3B13; 3BJI; 3BWD; 3EG5; 3GCG; 3KZ1; 3LW8; 3LWN; 3LXR; 3MSX; 3Q3J; 3QBV; 3REF; 3REG; 3RYT; 3SBD; 3SBE; 3SU8; 3SUA; 3T06; 3TH5; 3TVD; 3VHL; 4D0N; 4DID; 4DVG; 4F38; 4GZL; 4GZM; 4ITR; 4JS0; 4MIT; 4U5X; 4XH9; 4XOI; 4XSG; 4XSH; 4YC7; 4YDH; 4YON; 5A0F; 5BWM; 5C2J; 5C2K; 5C4M; 5CJP; 5EZ6; 5FI0; 5FI1; 5FR1; 5FR2; 5HPY; 5HZH; 5HZK; 5IRC; 5JCP; 5JHG; 5JHH; 5M6X; 5M70; 5N6O; 5O33; 5QQD; 5QQE; 5QQF; 5QQG; 5QQH; 5QQI; 5QQJ; 5QQK; 5QQL; 5QQM; 5QQN; 5QU9; 5UPK; 5UPL; 5ZHX; 6AGP; 6AJ4; 6AJL; 6BC0; 6BC1; 6BCA; 6BCB; 6HXU; 6KX2; 6KX3; 6R3V; 6SGE; 6SIU; 6TGC; 6TKY; 6TKZ; 6TM1; 6UKA; 6V6M; 6V6U; 6V6V; 6X1G; 7AJK; 7DPA; 7G80; 7G81; 7G82; 7G83; 7G84; 7G85; 7G86; 7G87; 7G88; 7G89; 7G8A; 7G8B; 7G8C; 7G8D; 7G8E; 7G8F; 7G8G; 7G8H; 7G8I; 7G8J; 7G8K; 7G8L; 7G8M; 7G8N; 7G8O; 7G8P; 7G8Q; 7G8R; 7G8S; 7G8T; 7G8U; 7G8V; 7G8W; 7G8X; 7G8Y; 7G8Z; 7G90; 7G91; 7G92; 7G93; 7G94; 7G95; 7G96; 7G97; 7G98; 7G99; 7G9A; 7G9B; 7G9C; 7G9D; 7G9E; 7G9F; 7G9G; 7G9H; 7G9I; 7G9J; 7KDC; 7QSC; 7QTM; 7S0Y; 7SJ4; 7U2P; 7USD; 7USE; 7WZA; 7WZC; 7XQV; 7Y4A; 8BNT; 8ETD; 8FC7; 8FC9; 8FCB; 8FPW; 8FPX; 8GI3; 8GI6; 8I5F; 8I5V; 8I5W; 8JVJ; 8Q0N; 8T1C; 8WEJ; 8WLA; 8XM7; 8ZJ2; 8ZJI; 8ZJJ; 8ZJK; 8ZJL; 8ZJM; 9AX5 » more |