ProRule PRU00768
General rule information
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| Accession | PRU00768 |
| Dates | 2-MAR-2009 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50079; NLS_BP |
Name | Bipartite nuclear localization signal |
| Function | The uptake of protein by the nucleus is extremely selective and nuclear proteins must therefore contain within their final structure a signal that specifies selective accumulation in the nucleus. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9Y6Y1 (CMTA1_HUMAN); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0005634; Cellular component:nucleus |
Features
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| From: PS50079 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOTIF | 1-1 | 7 | /note="Nuclear localization signal #" | |||||||||
Additional information
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| Size range | 15-20 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.