ProRule PRU00798
General rule information
[?]
| PURL | https://purl.expasy.org/prosite/rule/PRU00798 |
| Accession | PRU00798 |
| Dates | 20-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51465; KAZAL_2 |
Name | Kazal domain |
| Function | Kazal-type inhibitors represent the most studied canonical proteinase inhibitors. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | P00995 (ISK1_HUMAN); |
Propagated annotation
[?]
Keywords
[?]
| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
| Protease inhibitor | |
| Serine protease inhibitor | |
Gene Ontology
[?]
| GO:0010466; Biological process:negative regulation of peptidase activity |
| GO:0004867; Molecular function:serine-type endopeptidase inhibitor activity |
Cross-references
[?]
| PROSITE | PS00282; KAZAL_1; 1; |
Features
[?]
| From: PS51465 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Kazal-like #" | |||||||||
| SITE | 15 | 16 | /note="Reactive bond" | |||||||||
| DISULFID | 7 | 36 | disulf | C-x*-C | ||||||||
| DISULFID | 13 | 32 | disulf | C-x*-C | ||||||||
| DISULFID | 21 | 53 | disulf | C-x*-C | ||||||||
Additional information
[?]
| Size range | 28-76 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-9 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Eukaryota [388] All [ 388 ]
- Retrieve set of proteins with 3D structure for this domain