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annotation rule: PRU00808

General rule information [?]

Accession PRU00808
Dates 8-JUL-2013 (Created)
27-OCT-2018 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51475; PROTEASOME_ALPHA_2
Name Proteasome alpha-type subunit
Function Subunits that belong to the alpha-type group are proteins of from 210 to 290 amino acids that share a number of conserved sequence regions.

Propagated annotation [?]


Description [?]

+ RecName: EC=3.4.25.1;

Comments [?]

Catalytic activity Reaction=Cleavage of peptide bonds with very broad specificity.; EC=3.4.25.1;.
Similarity Belongs to the peptidase T1A family.

Cross-references [?]

PROSITE PS00388; PROTEASOME_A_1; 1;

Gene Ontology [?]

GO:0004298; Molecular function: threonine-type endopeptidase activity.
GO:0019773; Cellular component: proteasome core complex, alpha-subunit complex.

Keywords [?]


Additional information [?]

Size range 166-239 amino acids
Related rules None
Repeats 1
Topology Undefined
Example B8GEZ3 (PSA_METPE)
Scope
Eukaryota
Bacteria; Actinobacteria
Archaea
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]