We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00809
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00809
General rule information
[?]
| Accession | PRU00809 |
| Dates | 09-JUL-2013 (Created)
13-JAN-2023 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51476; PROTEASOME_BETA_2 |
Name | Proteasome beta-type subunit |
| Function | Subunits that belong to the beta-type group are proteins of from 190 to 290 amino acids that share a number of conserved sequence regions. |
| Scope(s) |
Bacteria Eukaryota Archaea |
| Example(s) | B9IVB9; |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| case <FTGroup:1> | |
| Protein name | + RecName: EC=3.4.25.-; |
Comments
[?]
| SUBCELLULAR LOCATION | Cytoplasm. |
| case <OC:Bacteria> and not <AnyFeature:PS00854> | |
| SIMILARITY | Belongs to the peptidase T1B family. HslV subfamily. |
| else | |
| SIMILARITY | Belongs to the peptidase T1B family. |
| end case | |
Keywords
[?]
| Hydrolase | |
| Protease | |
| Threonine protease | |
| end case | |
| Cytoplasm | |
Gene Ontology
[?]
| case <FTGroup:1> | |
| GO:0004298; Molecular function:threonine-type endopeptidase activity | |
Cross-references
[?]
| PROSITE | PS00854; PROTEASOME_BETA_1; 1; |
Features
[?]
| From: PS51476 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 2 | 2 | T | 1 | ||||||||
| ACT_SITE | 18 | 18 | [DE] | 1 | ||||||||
| ACT_SITE | 34 | 34 | K | 1 | ||||||||
Additional information
[?]
| Size range | 92-209 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Archaea [118] Bacteria [496] Eukaryota [124] All [ 738 ]
- Retrieve set of proteins with 3D structure for this domain