We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00829
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00829
General rule information
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| Accession | PRU00829 |
| Dates | 22-DEC-2010 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51496; CVC |
Name | CVC domain |
| Function | The CVC (standing for Chx10/Vsx-1 and ceh-10) domain consists of approximately 50-60 amino acid residues. The CVC domain is predicted to influence transcriptional regulation through DNA-binding, protein-protein interaction and/or protein degradation processes. It is possible that the CVC domain is necessary for protein folding or protein-protein interactions because this domain is hydrophobic. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | Q9IAL2; |
Propagated annotation
[?]
Features
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| From: PS51496 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="CVC #" | |||||||||
Additional information
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| Size range | 43-85 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [13] All [ 13 ]
- Retrieve set of proteins with 3D structure for this domain