PROSITE entry PS51496
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51496 |
| Entry name [info] | CVC |
| Accession [info] | PS51496 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2010 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51496 |
| Associated ProRule [info] | PRU00829 |
Name and characterization of the entry
| Description [info] | CVC domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=54; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=49; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.9688087; R2=0.0082100; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6134.7841797; R2=2.0229120; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=918; H_SCORE=7992; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=674; H_SCORE=7498; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-14; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='K'; M=-18, 0,-67, 0, -1,-68,-18,-11,-18, 55,-38, 8, 9,-18, 8, 36, 2, 3,-28,-42,-48, -1; /M: SY='C'; M=-18,-28, 28,-35,-38,-50,-32,-18,-13,-18,-41,-24,-23,-21,-31, 0, -3,-12,-11,-52,-25,-33; /M: SY='W'; M=-70,-60,-90,-80,-90, 0,-80,-30,-60,-40,-20,-50,-50,-70,-60, 20,-30,-60,-80,180,-10,-70; /M: SY='G'; M= 10, 0,-40, 0, 0,-60, 60,-30,-30,-20,-50,-40, 0,-10,-20,-40, 10, 0,-20,-80,-60,-10; /M: SY='R'; M= -7, -2,-45, -6, -6,-55, 7, -1,-25, 13,-43,-21, 3, -8, -1, 14, 0, -5,-26,-37,-50, -2; /M: SY='S'; M= 10, 10, 0, 0, 0,-40, 10,-10,-20, 0,-40,-20, 10, 10,-10,-10, 20, 20,-10,-30,-30,-10; /M: SY='T'; M= 10, 6,-13, 0, -4,-40, 6,-14,-11, 0,-31,-16, 6, 6,-10,-10, 20, 29, -6,-43,-30,-10; /M: SY='I'; M= -6,-27,-28,-27,-22,-13,-24,-28, 42,-18, 15, 19,-17,-24,-26,-20,-13, 0, 39,-69,-28,-22; /M: SY='M'; M=-20,-30,-60,-40,-30, 0,-40,-30, 20, 10, 40, 80,-20,-30,-10,-10,-20,-10, 20,-50,-30,-20; /M: SY='A'; M= 30, 0,-30, 0, 0,-40, 10,-20,-10,-20,-20,-20, 0, 10,-10,-20, 10, 10, 0,-70,-40, 0; /M: SY='E'; M= 0, 30,-70, 40, 50,-70, 0, 0,-30, 0,-40,-30, 20,-10, 30,-20, 0,-10,-20,-90,-50, 40; /M: SY='Y'; M=-40,-40, 0,-50,-50, 70,-60, 0,-20,-50,-20,-30,-20,-60,-50,-50,-30,-30,-30,-10,110,-50; /M: SY='G'; M= 10, 0,-40, 0, 0,-60, 60,-30,-30,-20,-50,-40, 0,-10,-20,-40, 10, 0,-20,-80,-60,-10; /M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30; /M: SY='Y'; M=-40,-40, 0,-50,-50, 70,-60, 0,-20,-50,-20,-30,-20,-60,-50,-50,-30,-30,-30,-10,110,-50; /M: SY='G'; M= 10, 0,-40, 0, 0,-60, 60,-30,-30,-20,-50,-40, 0,-10,-20,-40, 10, 0,-20,-80,-60,-10; /M: SY='A'; M= 30, 0,-30, 0, 0,-40, 10,-20,-10,-20,-20,-20, 0, 10,-10,-20, 10, 10, 0,-70,-40, 0; /M: SY='M'; M=-20,-30,-60,-40,-30, 0,-40,-30, 20, 10, 40, 80,-20,-30,-10,-10,-20,-10, 20,-50,-30,-20; /M: SY='V'; M= 0,-30,-20,-30,-20,-20,-20,-30, 40,-30, 20, 20,-20,-20,-30,-30,-10, 0, 50,-80,-30,-20; /M: SY='R'; M=-20,-10,-40,-20,-20,-50,-40, 20,-20, 40,-40,-10, 0, 0, 10, 70,-10,-10,-30, 20,-50, 0; /M: SY='H'; M=-20, 10,-40, 0, 0,-20,-30, 80,-30,-10,-30,-30, 20,-10, 30, 20,-10,-20,-30,-30, 0, 20; /M: SY='C'; M= -1, -6, 33,-16,-19,-45, -4,-18,-23,-19,-48,-31, -6, -4,-26,-18, 15, 6,-13,-46,-22,-26; /M: SY='L'; M=-15,-35,-49,-39,-35, 15,-39,-30, 41,-29, 44, 29,-29,-30,-25,-29,-29, -9, 31,-41,-20,-30; /M: SY='P'; M= 10,-10,-40,-20,-10,-60,-10,-10,-30,-20,-30,-30,-10, 70, 0, 0, 10, 0,-20,-70,-60,-10; /M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30; /M: SY='P'; M= 10,-10,-40,-20,-10,-60,-10,-10,-30,-20,-30,-30,-10, 70, 0, 0, 10, 0,-20,-70,-60,-10; /I: I=-5; MI=0; MD=-11; IM=0; DM=-11; /M: SY='E'; M= -2, 32,-66, 41, 42,-70, -2, -1,-29, 5,-44,-31, 23,-15, 25,-15, 0, -5,-25,-82,-50, 33; /M: SY='T'; M= 10, 5,-14, 0, -5,-40, 5,-15,-11, 0,-31,-15, 5, 5,-10,-10, 20, 29, -5,-44,-30,-10; /M: SY='I'; M= -7,-30,-27,-30,-27, 2,-27,-30, 55,-23, 20, 20,-20,-27,-30,-23,-17, 0, 43,-65,-23,-27; /M: SY='L'; M=-15,-35,-58,-42,-35, 13,-42,-29, 27,-32, 52, 32,-32,-27,-21,-33,-31,-11, 23,-32,-21,-28; /M: SY='K'; M=-11, 11,-61, 11, 7,-58, -7, 0,-21, 36,-41, -4, 17,-16, 8, 20, 4, 0,-26,-46,-40, 3; /M: SY='S'; M= 10, 10, 0, 0, 0,-40, 10,-10,-20, 0,-40,-20, 10, 10,-10,-10, 20, 20,-10,-30,-30,-10; /M: SY='A'; M= 27, 0,-31, 0, -1,-41, 13,-21,-11,-18,-22,-21, 0, 8,-11,-21, 11, 12, -1,-70,-41, -1; /M: SY='K'; M=-13, 9,-69, 11, 14,-63,-15, -8,-21, 31,-33, -3, 11,-18, 14, 13, -3, -4,-24,-55,-48, 11; /I: I=-15; MD=-32; /M: SY='D'; M= 5, 21,-46, 25, 23,-54, 12, -6,-24, -4,-39,-30, 16, -9, 7,-19, 5, 0,-19,-68,-42, 15; D=-15; /I: I=-15; MI=-32; IM=-32; DM=-32; /M: SY='G'; M= 8, 14,-40, 14, 10,-51, 28,-10,-24, -7,-44,-30, 13, -7, -6,-22, 10, 3,-18,-66,-43, 0; /I: I=-13; MI=0; MD=-27; IM=0; DM=-27; /M: SY='L'; M= -9,-18,-39,-23,-19, 0,-24,-15, 10,-16, 24, 19,-16,-11,-10,-17,-16, -8, 9,-26,-18,-15; D=-13; /I: I=-13; DM=-27; /M: SY='M'; M= -7, -9,-38,-10, -4,-17,-19, -8, 4, -5, 10, 17, -7,-13, 2,-10,-11, -6, 6,-40,-25, 0; D=-13; /I: I=-13; DM=-27; /M: SY='E'; M= 4, 17,-55, 23, 25,-65, 24,-11,-30, -8,-45,-35, 12,-11, 8,-26, 4, -4,-23,-81,-54, 16; /M: SY='S'; M= 10, 5, 1, -3, -4,-41, 7,-13,-19, -6,-38,-22, 5, 7,-13,-13, 18, 17, -9,-39,-30,-12; /M: SY='C'; M=-16,-39, 63,-46,-48,-46,-29,-35, -6,-53,-37,-31,-36,-29,-52,-35, -2,-17, 4,-85,-13,-48; /M: SY='A'; M= 30, 0,-30, 0, 0,-40, 10,-20,-10,-20,-20,-20, 0, 10,-10,-20, 10, 10, 0,-70,-40, 0; /M: SY='P'; M= 10,-10,-40,-20,-10,-60,-10,-10,-30,-20,-30,-30,-10, 70, 0, 0, 10, 0,-20,-70,-60,-10; /M: SY='W'; M=-70,-60,-90,-80,-90, 0,-80,-30,-60,-40,-20,-50,-50,-70,-60, 20,-30,-60,-80,180,-10,-70; /M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30; /M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30; /I: I=-5; MI=0; MD=-11; IM=0; DM=-11; /M: SY='G'; M= 9, 0,-40, -1, -1,-60, 56,-28,-30,-18,-50,-39, 0,-10,-19,-35, 9, 0,-20,-76,-60,-10; /M: SY='M'; M=-20,-30,-60,-40,-30, 0,-40,-30, 20, 10, 40, 80,-20,-30,-10,-10,-20,-10, 20,-50,-30,-20; /M: SY='H'; M=-20, 10,-40, 0, 0,-20,-30, 80,-30,-10,-30,-30, 20,-10, 30, 20,-10,-20,-30,-30, 0, 20; /M: SY='K'; M=-20, -2,-64, -4, -4,-66,-24, -4,-20, 56,-40, 6, 8,-16, 10, 46, -2, -2,-30,-28,-50, 0; /M: SY='K'; M=-20, 0,-70, 0, 0,-70,-20,-10,-20, 60,-40, 10, 10,-20, 10, 40, 0, 0,-30,-40,-50, 0; /M: SY='S'; M= 10, 10, 0, 0, 0,-40, 10,-10,-20, 0,-40,-20, 10, 10,-10,-10, 20, 20,-10,-30,-30,-10; /M: SY='M'; M= -7,-22,-45,-28,-24, -7,-26,-26, 18,-14, 24, 28,-18,-19,-17,-21,-13, 2, 17,-46,-26,-20; /M: SY='E'; M= 1, 19,-62, 25, 32,-62, 11, -9,-26, -4,-37,-25, 13,-12, 15,-24, 1, -7,-18,-84,-51, 23; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 13 in 13 different sequences |
| Number of true positive hits | 13 in 13 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | CVC |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
13 sequences
HM10_CAEEL (P41935), VSX1_BOVIN (Q9GMA3), VSX1_CARAU (Q90277), VSX1_CHICK (Q9IAL2), VSX1_DANRE (O42250), VSX1_HUMAN (Q9NZR4), VSX1_MOUSE (Q91V10), VSX1_XENLA (Q0P031), VSX2_CHICK (Q9IAL1), VSX2_DANRE (O42477), VSX2_HUMAN (P58304), VSX2_MOUSE (Q61412), VSX2_ORYLA (Q9I9A3)» more
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