ProRule PRU00849

General rule information [?]

Accession PRU00849
Dates 11-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51516; SOX_C
Name Sox C-terminal domain
Function Bioinformatic analysis of the C-termini of subgroup F Sox family members from different species including humans, mice, rat, chicken and Xenopus revealed three conserved blocks including highly conserved residues. They were termed proline, charged, and serine according to the predominance of the respective amino acids. The charged block comprises a strong transactivating domain.
Scope(s) Eukaryota
Example(s) O42342 (SOX7_XENLA);

Propagated annotation [?]

Features [?]

From: PS51516
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Sox C-terminal #"

Additional information [?]

Size range 105-151 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]