ProRule PRU00849
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00849 |
| Accession | PRU00849 |
| Dates | 11-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51516; SOX_C |
Name | Sox C-terminal domain |
| Function | Bioinformatic analysis of the C-termini of subgroup F Sox family members from different species including humans, mice, rat, chicken and Xenopus revealed three conserved blocks including highly conserved residues. They were termed proline, charged, and serine according to the predominance of the respective amino acids. The charged block comprises a strong transactivating domain. |
| Scope(s) |
Eukaryota Euteleostomi |
| Example(s) | O42342 (SOX7_XENLA); |
Propagated annotation
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Features
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| From: PS51516 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Sox C-terminal #" | |||||||||
Additional information
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| Size range | 105-151 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [19] All [ 19 ]
- Retrieve set of proteins with 3D structure for this domain