We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00852
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00852
General rule information
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| Accession | PRU00852 |
| Dates | 22-MAR-2011 (Created)
27-JUN-2022 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51519; RWP_RK |
Name | RWP-RK domain |
| Function | The RWP-RK putative DNA-binding domain has been named after its most striking feature, the invariant R-W-P-x-R-K motif. It could be involved in the regulation of genes controlled by nitrogen status. |
| Scope(s) |
Eukaryota Magnoliopsida |
| Example(s) | Q9LE38; |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
| GO:0005634; Cellular component:nucleus |
| GO:0003677; Molecular function:DNA binding |
Features
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| From: PS51519 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="RWP-RK #" | |||||||||
Additional information
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| Size range | 72-105 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [17] All [ 17 ]
- Retrieve set of proteins with 3D structure for this domain