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|
| annotation rule: PRU00855 |
General rule information
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| Accession | PRU00855 |
| Dates | 4-FEB-2011 (Created) 21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
| Predictors | PROSITE; PS51522; ZF_NANOS |
| Name | Zinc finger nanos-type |
| Function | The nanos-type zinc finger has two conserved Cys-Cys-His-Cys (CCHC)- type zinc-finger motifs that are indispensable for nanos function. |
Propagated annotation
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Comments
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case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C> and <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
| Domain | The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein. |
end case
| Similarity | Belongs to the nanos family. |
Gene Ontology
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case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0006417; Biological process: regulation of translation.
GO:0003723; Molecular function: RNA binding.
GO:0003723; Molecular function: RNA binding.
Keywords
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case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
end case
case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
end case
Features
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case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C> and <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
| From: PS51522 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ZN_FING | from | to | Nanos-type # | |||||||||
else case <Feature:PS51522:2=[CH]> and <Feature:PS51522:5=[CH]> and <Feature:PS51522:18=[HC]> and <Feature:PS51522:29=[CH]> and <Feature:PS51522:37=[CH]> and <Feature:PS51522:40=[CH]> and <Feature:PS51522:48=[HC]> and <Feature:PS51522:53=[CH]>
else
end case
case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C>
end case
case <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
end case
Additional information
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| Size range | 45-65 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | P60323 (NANO3_HUMAN) |
| Scope | Eukaryota; Metazoa |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Eukaryota [11]
- Retrieve set of proteins with 3D structure for this domain