General rule information
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Accession |
PRU00855 |
Dates |
4-FEB-2011 (Created) 16-DEC-2016 (Last updated, Version 5) |
Predictors |
PROSITE; PS51522; ZF_NANOS
|
Name |
Zinc finger nanos-type |
Function |
The nanos-type zinc finger has two conserved Cys-Cys-His-Cys (CCHC)- type zinc-finger motifs that are indispensable for nanos function. |
Propagated annotation
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case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C> and <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
Domain |
The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein. |
end case
Similarity |
Belongs to the nanos family. |
case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
end case
GO:0006417; Biological process: regulation of translation.
GO:0003723; Molecular function: RNA binding.
case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
end case
case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
end case
case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C> and <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
From: PS51522 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ZN_FING
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from
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to
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Nanos-type #
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else case <Feature:PS51522:2=[CH]> and <Feature:PS51522:5=[CH]> and <Feature:PS51522:18=[HC]> and <Feature:PS51522:29=[CH]> and <Feature:PS51522:37=[CH]> and <Feature:PS51522:40=[CH]> and <Feature:PS51522:48=[HC]> and <Feature:PS51522:53=[CH]>
ZN_FING
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from
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to
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Nanos-type #; atypical
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else
ZN_FING
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from
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to
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Nanos-type #; degenerate
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end case
case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C>
end case
case <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
end case
Additional information
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Size range |
45-65 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
P60323 (NANO3_HUMAN) |
Scope |
Eukaryota; Metazoa |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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