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annotation rule: PRU00871

General rule information [?]

Accession PRU00871
Dates 8-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain
Predictors PROSITE; PS51538; AV_CP
Name Arterivirus nsp2 cysteine protease (AV CP) domain
Function The AV CP is an unusual Cys protease with amino acid sequence similarities to both papain-like and chymotrypsin-like proteases. The catalytic dyad is composed of Cys and His residues. The AV CP domain forms peptidase family C33.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0008234; Molecular function: cysteine-type peptidase activity.
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0019082; Biological process: viral protein processing.

Keywords [?]

end case


Features [?]

From: PS51538
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase C33 #        
ACT_SITE     10     10       For Nsp2 cysteine proteinase activity     C   1
ACT_SITE     79     79       For Nsp2 cysteine proteinase activity     H   1

Additional information [?]

Size range 90-118 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9YN02 (RPOA_PRRS1)
Scope
Viruses; Arteriviridae
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]