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ProRule PRU00871


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PURL: https://purl.expasy.org/prosite/rule/PRU00871
General rule information [?]

Accession PRU00871
Dates 08-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51538; AV_CP
Name Arterivirus nsp2 cysteine protease (AV CP) domain
Function The AV CP is an unusual Cys protease with amino acid sequence similarities to both papain-like and chymotrypsin-like proteases. The catalytic dyad is composed of Cys and His residues. The AV CP domain forms peptidase family C33.
Scope(s) Viruses
Arteriviridae
Example(s) Q9YN02 (RPOA_PRRS1);

Propagated annotation [?]

Keywords [?]

Hydrolase
Protease
Thiol protease
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008234; Molecular function:cysteine-type peptidase activity
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0019082; Biological process:viral protein processing

Features [?]

From: PS51538
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase C33 #"
ACT_SITE 10 10 /note="For Nsp2 cysteine proteinase activity" C 1
ACT_SITE 79 79 /note="For Nsp2 cysteine proteinase activity" H 1

Additional information [?]

Size range 90-118 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]