ProRule PRU00871

General rule information [?]

Accession PRU00871
Dates 8-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51538; AV_CP
Name Arterivirus nsp2 cysteine protease (AV CP) domain
Function The AV CP is an unusual Cys protease with amino acid sequence similarities to both papain-like and chymotrypsin-like proteases. The catalytic dyad is composed of Cys and His residues. The AV CP domain forms peptidase family C33.
Scope(s) Viruses
Example(s) Q9YN02 (RPOA_PRRS1);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0008234; Molecular function:cysteine-type peptidase activity
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0019082; Biological process:viral protein processing

Features [?]

From: PS51538
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase C33 #"
ACT_SITE 10 10 /note="For Nsp2 cysteine proteinase activity" C 1
ACT_SITE 79 79 /note="For Nsp2 cysteine proteinase activity" H 1

Additional information [?]

Size range 90-118 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]