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annotation rule: PRU00872

General rule information [?]

Accession PRU00872
Dates 31-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51539; AV_PCP_ALPHA
Name Arterivirus papain-like cysteine protease alpha (PCPalpha) domain
Function The PCPalpha domain mediates the nsp1alpha|1beta cleavage.

Propagated annotation [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0004197; Molecular function: cysteine-type endopeptidase activity.

Keywords [?]

end case

Features [?]

case <FTGroup:1>
From: PS51539
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase C31 #        
DOMAIN     from     to       Peptidase C31 (inactive) #        
end case

ACT_SITE     8     8       For Nsp1-alpha papain-like cysteine proteinase activity     C   1
ACT_SITE     77     77       For Nsp1-alpha papain-like cysteine proteinase activity     H   1
case <FTGroup:1>
SITE     to     to+1       Cleavage; by autolysis        
end case

Additional information [?]

Size range 81-123 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9YN02 (RPOA_PRRS1)
Viruses; Arteriviridae
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Viruses [11]