ProRule PRU00872
General rule information
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| Accession | PRU00872 |
| Dates | 31-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51539; AV_PCP_ALPHA |
Name | Arterivirus papain-like cysteine protease alpha (PCPalpha) domain |
| Function | The PCPalpha domain mediates the nsp1alpha|1beta cleavage. |
| Scope(s) |
Viruses Arteriviridae |
| Example(s) | Q9YN02 (RPOA_PRRS1); |
Propagated annotation
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Keywords
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| Hydrolase | |
| Protease | |
| Thiol protease | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0016787; Molecular function:hydrolase activity | |
| GO:0008233; Molecular function:peptidase activity | |
| GO:0004197; Molecular function:cysteine-type endopeptidase activity | |
Features
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| From: PS51539 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <FTGroup:1> | ||||||||||||
| DOMAIN | from | to | /note="Peptidase C31 #" | |||||||||
| else | ||||||||||||
| DOMAIN | from | to | /note="Peptidase C31 (inactive) #" | |||||||||
| end case | ||||||||||||
| ACT_SITE | 8 | 8 | /note="For Nsp1-alpha papain-like cysteine proteinase activity" | C | 1 | |||||||
| ACT_SITE | 77 | 77 | /note="For Nsp1-alpha papain-like cysteine proteinase activity" | H | 1 | |||||||
| case <FTGroup:1> | ||||||||||||
| SITE | to | to+1 | /note="Cleavage; by autolysis" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 81-123 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [12] All [ 12 ]
- Retrieve set of proteins with 3D structure for this domain