ProRule PRU00872

General rule information [?]

Accession PRU00872
Dates 31-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51539; AV_PCP_ALPHA
Name Arterivirus papain-like cysteine protease alpha (PCPalpha) domain
Function The PCPalpha domain mediates the nsp1alpha|1beta cleavage.
Scope(s) Viruses
Example(s) Q9YN02 (RPOA_PRRS1);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0004197; Molecular function:cysteine-type endopeptidase activity

Features [?]

From: PS51539
Key From To Description Tag Condition FTGroup
case <FTGroup:1>
DOMAIN from to /note="Peptidase C31 #"
DOMAIN from to /note="Peptidase C31 (inactive) #"
end case
ACT_SITE 8 8 /note="For Nsp1-alpha papain-like cysteine proteinase activity" C 1
ACT_SITE 77 77 /note="For Nsp1-alpha papain-like cysteine proteinase activity" H 1
case <FTGroup:1>
SITE to to+1 /note="Cleavage; by autolysis"
end case

Additional information [?]

Size range 81-123 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]