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annotation rule: PRU00873

General rule information [?]

Accession PRU00873
Dates 31-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51540; AV_PCP_BETA
Name Arterivirus papain-like cysteine protease beta (PCPbeta) domain
Function The PCPbeta domain mediates the nsp1beta|2 cleavage.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0004197; Molecular function: cysteine-type endopeptidase activity.

Keywords [?]

end case


Features [?]

case <FTGroup:1>
From: PS51540
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase C32 #        
else
DOMAIN     from     to       Peptidase C32 (inactive) #        
end case

ACT_SITE     8     8       For Nsp1-beta papain-like cysteine proteinase activity     C   1
ACT_SITE     73     73       For Nsp1-beta papain-like cysteine proteinase activity     H   1
case <FTGroup:1> and <Feature:PS51540:113=Y>
SITE     to     to+1       Cleavage; by autolysis     G-[GA]  
else case <FTGroup:1>
SITE     to     to+1       Cleavage; by autolysis        
end case


Additional information [?]

Size range 94-131 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9YN02 (RPOA_PRRS1)
Scope
Viruses; Arteriviridae
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Viruses [11]