ProRule PRU00873

General rule information [?]

Accession PRU00873
Dates 31-MAY-2011 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51540; AV_PCP_BETA
Name Arterivirus papain-like cysteine protease beta (PCPbeta) domain
Function The PCPbeta domain mediates the nsp1beta|2 cleavage.
Scope(s) Viruses
Example(s) Q9YN02 (RPOA_PRRS1);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0004197; Molecular function:cysteine-type endopeptidase activity

Features [?]

From: PS51540
Key From To Description Tag Condition FTGroup
case <FTGroup:1>
DOMAIN from to /note="Peptidase C32 #"
DOMAIN from to /note="Peptidase C32 (inactive) #"
end case
ACT_SITE 8 8 /note="For Nsp1-beta papain-like cysteine proteinase activity" C 1
ACT_SITE 73 73 /note="For Nsp1-beta papain-like cysteine proteinase activity" H 1
case <FTGroup:1> and <Feature:PS51540:113=Y>
SITE to to+1 /note="Cleavage; by autolysis" G-[GA]
else case <FTGroup:1>
SITE to to+1 /note="Cleavage; by autolysis"
end case

Additional information [?]

Size range 94-131 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]