General rule information
[?]
Accession |
PRU00896 |
Dates |
25-NOV-2011 (Created) 3-JAN-2022 (Last updated, Version 11) |
case <Length>=464> and <Length<=696>
Predictors |
PROSITE; PS51563; SAM_MTA70L_1
|
end case
Names |
N6-adenosine-methyltransferase catalytic subunit (EC=2.1.1.348); N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) |
Function |
The N6-methyltransferase complex methylates adenosine residues at the N(6) position of some RNAs. |
Propagated annotation
[?]
Catalytic activity |
RHEA:55584: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.348
|
Similarity |
Belongs to the class I-like SAM-binding methyltransferase superfamily. MT-A70-like family. |
GO:0003723; Molecular function: RNA binding.
GO:0016422; Molecular function: mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity.
GO:0001734; Molecular function: mRNA (N6-adenosine)-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0001510; Biological process: RNA methylation.
Additional information
[?]
Size range |
unlimited amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
F1R777 (MTA70_DANRE) |
Scope |
Eukaryota |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]
UniProtKB/Swiss-Prot sets