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| annotation rule: PRU00896 |
General rule information
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| Accession | PRU00896 |
| Dates | 25-NOV-2011 (Created) 3-JAN-2022 (Last updated, Version 11) |
| Data class | Domain |
case <Length>=464> and <Length<=696>
| Predictors | PROSITE; PS51563; SAM_MTA70L_1 |
end case
| Names | N6-adenosine-methyltransferase catalytic subunit (EC=2.1.1.348); N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) |
| Function | The N6-methyltransferase complex methylates adenosine residues at the N(6) position of some RNAs. |
Propagated annotation
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Description
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| + RecName: EC 2.1.1.348; |
Comments
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| Catalytic activity | RHEA:55584: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.348 |
| Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. MT-A70-like family. |
Gene Ontology
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GO:0003723; Molecular function: RNA binding.
GO:0016422; Molecular function: mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity.
GO:0001734; Molecular function: mRNA (N6-adenosine)-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0001510; Biological process: RNA methylation.
GO:0016422; Molecular function: mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity.
GO:0001734; Molecular function: mRNA (N6-adenosine)-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0001510; Biological process: RNA methylation.
Keywords
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Additional information
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| Size range | unlimited amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | F1R777 (MTA70_DANRE) |
| Scope | Eukaryota |
| Comments | None |
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UniProtKB rule member sequences
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