General rule information
21-NOV-2019 (Last updated, Version 8)
case <Length>=242> and <Length<=362>
||PROSITE; PS51564; SAM_ICMT
||Protein-S-isoprenylcysteine O-methyltransferase (EC 18.104.22.168) |
|| Protein-S-isoprenylcysteine O-methyltransferase (EC 22.214.171.124) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to a protein C-terminal S-farnesyl-L-cysteine to form a protein C-terminal S- farnesyl-L-cysteine methyl ester and S-adenosyl-L-homocysteine. |
||RHEA:21672: [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine
||Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
; Molecular function: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity.
; Biological process: methylation.
; Biological process: S-adenosylmethionine metabolic process.
||unlimited amino acids
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distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see prosite_license.html
UniProtKB rule member sequences