General rule information
21-NOV-2019 (Last updated, Version 14)
||PROSITE; PS51565; SAM_MT85_SETD3
||SETD3 actin-histidine N-methyltransferase (EC 18.104.22.168) |
|| SETD3 Actin-histidine N-methyltransferase (EC 22.214.171.124) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to L-histidine-[actin] to form N(tele)-methyl-L-histidine-[actin] and S-adenosyl-L-homocysteine. |
||RHEA:19369: L-histidyl-[protein] + S-adenosyl-L-methionine = H(+) + N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine
||Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
; Biological process: peptidyl-histidine methylation.
; Biological process: actin modification.
||unlimited amino acids
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UniProtKB rule member sequences