ProRule PRU00931

Accession	PRU00931
Dates	14-DEC-2011 (Created) 21-NOV-2019 (Last updated, Version 12)
Data class	Domain;
Predictors	PROSITE; PS51599; SAM_PEMT_PEM2
Name	Phospholipid methyltransferases (EC 2.1.1.17 and EC=2.1.1.71) family
Function	Phosphatidylethanolamine N-methyltransferase (EC 2.1.1.17) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to phosphatidylethanolamine to form phosphatidyl-N-methylethanolamine and S- adenosyl-L-homocysteine. Phosphatidyl-N-methylethanolamine N-methyltransferase (EC 2.1.1.71) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to phosphatidyl-N-methylethanolamine to form phosphatidyl-N- dimethylethanolamine and S-adenosyl-L-homocysteine. It also transfers a methyl group from S-adenosyl-L-methionine (SAM) to phosphatidyl-N- dimethylethanolamine to form phosphatidylcholine and S-adenosyl-L- homocysteine.
Scope(s)	Eukaryota
Example(s)	Q08388 (PEMT_RAT);