PRU00940
General rule information
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| Accession | PRU00940 |
| Dates | 14-DEC-2011 (Created) 26-JAN-2023 (Last updated, Version 11) |
| Data class | Domain |
| Predictors | PROSITE; PS51608; SAM_MT_UBIE |
| Name | UbiE family SAM-binding methyltransferase |
| Function | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase (EC 2.1.1.201) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to 2-methoxy-6-all-trans-polyprenyl-1,4 benzoquinol to form 6-methoxy-3-methyl- 2-all-trans polyprenyl-1,4-benzoquinol and S-adenosyl-L-homocysteine. |
Propagated annotation
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Description
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case not <OC:Eukaryota>
| + RecName: EC 2.1.1.163; |
end case
case <OC:Eukaryota> or <OC:Pseudomonadota>
| + RecName: EC 2.1.1.201; |
end case
Comments
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case not <OC:Eukaryota>
| Catalytic activity | RHEA:42640: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.163 |
end case
case <OC:Eukaryota> or <OC:Pseudomonadota>
| Catalytic activity | RHEA:28286: a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.201 |
end case
| Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. |
Cross-references
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Gene Ontology
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GO:0008757; Molecular function: S-adenosylmethionine-dependent methyltransferase activity.
case <OC:Eukaryota> or <OC:Pseudomonadota>
GO:0006744; Biological process: ubiquinone biosynthetic process.
end case
case not <OC:Eukaryota>
GO:0009234; Biological process: menaquinone biosynthetic process.
end case
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
Keywords
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case not <OC:Eukaryota>
end case
case <OC:Eukaryota> or <OC:Pseudomonadota>
end case
Additional information
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| Size range | unlimited amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q54VN2 (COQ5_DICDI) |
| Scope | Eukaryota |
| Comments | None |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Bacteria [394] Eukaryota [17] All [ 411 ]
- Retrieve set of proteins with 3D structure for this domain