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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00945


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00945
General rule information [?]

Accession PRU00945
Dates 14-DEC-2011 (Created)
19-NOV-2022 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS51613; SAM_MT_RRMJ
Name RrmJ-type ribose 2'-O-methyltransferase (EC 2.1.1.57) domain
Function mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57)
Scope(s) Eukaryota
Viruses
Alphabaculovirus
Example(s) D2HRF1;

Propagated annotation [?]

Identifier, protein and gene names [?]

case <FTGroup:1>
Protein name + RecName: EC=2.1.1.-;
end case

Keywords [?]

case <FTGroup:1>
Methyltransferase
S-adenosyl-L-methionine
Transferase
end case

Features [?]

From: PS51613
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="RrmJ-type SAM-dependent 2'-O-MTase #"
ACT_SITE 157 157 /note="Proton acceptor" K 1
BINDING 37 37 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"		 G 1
case <FTGroup:1>
BINDING 67 67 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"		 E
end case
BINDING 117 117 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"		 D 1

Additional information [?]

Size range 183-240 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]