ProRule PRU00986
General rule information
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| Accession | PRU00986 |
| Dates | 18-APR-2016 (Created)
3-NOV-2023 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51653; CV_ZBD |
Name | Coronaviridae zinc-binding (CV ZBD) domain |
| Function | The ZBD is comprised of about 80 to 100 residues, including 12 to 13 conserved Cys/His residues. It consists of a RING-like module and treble- cleft zinc finger, together coordinating three Zn atoms. |
| Scope(s) |
Viruses Coronaviridae |
| Example(s) | P0C6Y1 (R1AB_IBVB); |
Propagated annotation
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Keywords
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| Metal-binding | |
| Zinc | |
| end case | |
| Zinc-finger | |
Gene Ontology
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| case <FTGroup:1> or <FTGroup:2> or <FTGroup:3> | |
| GO:0046872; Molecular function:metal ion binding | |
| GO:0008270; Molecular function:zinc ion binding | |
Features
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| From: PS51653 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="CV ZBD #" | |||||||||
| BINDING | 5 | 5 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
| BINDING | 8 | 8 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
| BINDING | 16 | 16 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
C | 2 | |||||||
| BINDING | 19 | 19 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
C | 2 | |||||||
| BINDING | 26 | 26 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
| BINDING | 29 | 29 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
| BINDING | 33 | 33 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
H | 2 | |||||||
| BINDING | 39 | 39 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
H | 2 | |||||||
| BINDING | 50 | 50 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3" |
C | 3 | |||||||
| BINDING | 55 | 55 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3" |
[C] | 3 | |||||||
| BINDING | 72 | 72 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3" |
C | 3 | |||||||
| BINDING | 75 | 75 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3" |
[HC] | 3 | |||||||
Additional information
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| Size range | 72-94 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [34] All [ 34 ]
- Retrieve set of proteins with 3D structure for this domain