ProRule PRU00986

PURL	https://purl.expasy.org/prosite/rule/PRU00986
Accession	PRU00986
Dates	18-APR-2016 (Created) 3-NOV-2023 (Last updated, Version 7)
Data class	Domain;
Predictors	PROSITE; PS51653; CV_ZBD
Name	Coronaviridae zinc-binding (CV ZBD) domain
Function	The ZBD is comprised of about 80 to 100 residues, including 12 to 13 conserved Cys/His residues. It consists of a RING-like module and treble- cleft zinc finger, together coordinating three Zn atoms.
Scope(s)	Viruses Coronaviridae
Example(s)	P0C6Y1 (R1AB_IBVB);

From: PS51653
Key	From	To	Description	Tag	Condition	FTGroup
DOMAIN	from	to	/note="CV ZBD #"
BINDING	5	5	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		C	1
BINDING	8	8	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		C	1
BINDING	16	16	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		C	2
BINDING	19	19	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		C	2
BINDING	26	26	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		C	1
BINDING	29	29	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		C	1
BINDING	33	33	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		H	2
BINDING	39	39	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		H	2
BINDING	50	50	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		C	3
BINDING	55	55	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		[C]	3
BINDING	72	72	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		C	3
BINDING	75	75	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3"		[HC]	3