PRU00986

General rule information [?]

Accession	PRU00986
Dates	18-APR-2016 (Created) 19-NOV-2022 (Last updated, Version 6)

Data class

Domain

Predictors

PROSITE; PS51653; CV_ZBD

Name	Coronaviridae zinc-binding (CV ZBD) domain

Function

The ZBD is comprised of about 80 to 100 residues, including 12 to 13 conserved Cys/His residues. It consists of a RING-like module and treble- cleft zinc finger, together coordinating three Zn atoms.

Propagated annotation [?]

Gene Ontology [?]

case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>

GO:0046872; Molecular function: metal ion binding.
GO:0008270; Molecular function: zinc ion binding.

Keywords [?]

Metal-binding
Zinc

end case

Zinc-finger

Features [?]

From: PS51653

Key From To Description Tag Condition FTGroup

DOMAIN from to CV ZBD #

BINDING 5 5 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1 C 1

BINDING 8 8 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1 C 1

BINDING 16 16 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2 C 1

BINDING 19 19 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1 C 2

BINDING 26 26 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1 [CH] 1

BINDING 29 29 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2 [CH] 2

BINDING 33 33 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2 [CH] 2

BINDING 39 39 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2 [CH] 2

BINDING 50 50 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3 C 3

BINDING 55 55 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3 [CH] 3

BINDING 72 72 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3 C 3

BINDING 75 75 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#3 [CH] 3

Additional information [?]

Size range	72-94 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	P0C6Y1 (R1AB_IBVB)
Scope	Viruses; Coronaviridae
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Viruses [33]
Retrieve set of proteins with 3D structure for this domain